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MSH3

mutS homolog 3

Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.

Gene Name: mutS homolog 3
Synonyms: MSH3, DUP, DUC1, DUG, MRP1, MutS (E. coli) homolog 3, MutS homolog 3 (E. coli), HMSH3, Mismatch repair protein 1, Divergent upstream protein
Target Sequences: NM_002439

☰ Filters
Products
Antibodies (11)
Primary (11)
MSH3 (11)
Human (11)
Mouse (1)
Rat (1)
IHC (6)
IHC-P (2)
WB (10)
ELISA (3)
IF (1)
IP (2)
Peptide-ELISA (2)
rabbit (11)
Product Group
IHCPlus (1)
IgG (8)
polyclonal pc (11)
Unconjugated (11)
30-110 aa, N-terminal (1)
Ala80 (1)
N-Terminus (1)
aa1025-1075 (1)
aa1087-1137 (1)
aa51-100 (1)
No (11)
MSH3 Antibody - Anti-MRP1 / MSH3 antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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MSH3 Rabbit anti-Human Polyclonal (aa51-100) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
MSH3 Antibody - Immunohistochemical analysis of MSH3 staining in human colon cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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MSH3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$299
MSH3 Antibody - Staining HuvEc cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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MSH3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
MSH3 Antibody - Western blot of MSH3 antibody
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MSH3 Rabbit anti-Human Polyclonal (30-110 aa, N-terminal) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
MSH3 Rabbit anti-Human Polyclonal (Ala80) Antibody
Human
IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
Select
MSH3 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
MSH3 Antibody - Western blot analysis of extracts of various cell lines.
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MSH3 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
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MSH3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$351
MSH3 Antibody - Western blot analysis of extracts from HUVEC cells, using MSH3 antibody.
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MSH3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
MSH3 Antibody - Detection of human MSH3 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-MSH3 antibody used for WB at 0.1 µg/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
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MSH3 Rabbit anti-Human Polyclonal (aa1087-1137) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
Select
MSH3 Rabbit anti-Human Polyclonal (aa1025-1075) Antibody
Human
IP
Unconjugated
10 µg/$295; 100 µl/$514
Viewing 1-11 of 11 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).