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MSC / Musculin

musculin

MSC / Musculin is a transcriptional repressor capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro. The encoded protein also forms heterodimers with E2A proteins in vivo. This protein is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. This gene is a downstream target of the B-cell receptor signal transduction pathway.

Gene Name:	musculin
Synonyms:	MSC, ABF1, ABF-1, BHLHa22, Activated B-cell factor 1, Activated B-cell factor-1, Musculin, MYOR
Target Sequences:	NM_005098 NP_005089.2 O60682

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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