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Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.
Gene Name: | metallophosphoesterase 1 |
Synonyms: | MPPE1, Metallo phosphoesterase, Metallophosphoesterase 1, PGAP5 |
Target Sequences: | NM_023075 NP_075563.3 Q53F39 |
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