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MPG

N-methylpurine-DNA glycosylase

Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.

Gene Name: N-methylpurine-DNA glycosylase
Synonyms: MPG, 3-alkyladenine DNA glycosylase, ADPG, Anpg, AAG, APNG, CRA36.1, N-methylpurine-DNA glycosylase, PIG16, PIG11, MDG
Target Sequences: NM_002434 NP_002425.2 P29372

Publications (1)

1
Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression. Nicola P Montaldo, Diana L Bordin, Alessandro Brambilla, Marcel Rösinger, Sarah L Fordyce Martin, Karine Øian Bjørås, Stefano Bradamante, Per Arne Aas, Antonia Furrer, Lene C Olsen, Nicolas Kunath, Marit Otterlei, Pål Sætrom, Magnar Bjørås, Leona D Samson, Barbara van Loon. Nature communications. 2019 Nov;10:5460. [Full Text Article] [PubMed:31784530] [PMC:PMC6884549] Related Antibodies: LS-C133325.

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Products
Proteins (10)
Over-Expression Lysate (2)
Recombinant (8)
MPG (10)
No (10)
6His, C-terminus (1)
GST (1)
GST, N-terminus (1)
GST, N-terminus + His, C-terminus (1)
His (3)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (7)
Mouse (1)
Rat (1)
293T Cells (1)
E. coli (5)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Yeast (1)
Purified (2)
MPG Protein
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E. coli
6His, C-terminus
50 µg/$411; 250 µg/$985; 10 µg/$276
MPG Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
32.19 kDa
100 µg/$494
MPG Protein
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E. coli
GST, N-terminus + His, C-terminus
58.2 kDa
50 µg/$419
MPG Protein - 12.5% SDS-PAGE of human MPG stained with Coomassie Blue
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Wheat Germ Extract
GST
58.6 kDa
2 µg/$439
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Yeast
His
34.2 kD
100 µg/$446; 20 µg/$336; 1 mg/$1,460
MPG Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
32.19 kDa
20 µg/$150
MPG Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
MPG Protein - Recombinant N-Methylpurine DNA Glycosylase By SDS-PAGE
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E. coli
His
31.4 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
MPG Protein - Recombinant N-Methylpurine DNA Glycosylase By SDS-PAGE
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E. coli
His
34.8 kDa
10 µg/$278; 50 µg/$422; 100 µg/$677; 200 µg/$845; 1 mg/$1,938; 500 µg/$1,485; 5 mg/$2,955; 2 mg/$2,124
MPG Protein - Recombinant N-Methylpurine DNA Glycosylase By SDS-PAGE
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E. coli
His-T7
33.5 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).