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MPG

N-methylpurine-DNA glycosylase

Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.

Gene Name: N-methylpurine-DNA glycosylase
Synonyms: MPG, 3-alkyladenine DNA glycosylase, ADPG, Anpg, AAG, APNG, CRA36.1, N-methylpurine-DNA glycosylase, PIG16, PIG11, MDG
Target Sequences: NM_002434 NP_002425.2 P29372

Publications (1)

1
Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression. Nicola P Montaldo, Diana L Bordin, Alessandro Brambilla, Marcel Rösinger, Sarah L Fordyce Martin, Karine Øian Bjørås, Stefano Bradamante, Per Arne Aas, Antonia Furrer, Lene C Olsen, Nicolas Kunath, Marit Otterlei, Pål Sætrom, Magnar Bjørås, Leona D Samson, Barbara van Loon. Nature communications. 2019 Nov;10:5460. [Full Text Article] [PubMed:31784530] [PMC:PMC6884549] Related Antibodies: LS-C133325.

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MPG ELISA Kit
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0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).