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RAGE belongs to the MAP kinase superfamily. The gene was found to be regulated by caudal type transcription factor 2 (Cdx2) protein. The encoded protein, which is localized to epithelial cells in the intestinal crypt, may play a role in growth arrest and differentiation of cells of upper crypt and lower villus regions. Multiple alternatively spliced transcript variants encoding different isoforms have been observed for this gene.
Gene Name: | MOK protein kinase |
Family/Subfamily: | Protein Kinase , MAK |
Synonyms: | MOK, MOK kinase, MOK protein kinase, RAGE, RAGE1, RAGE-1, Renal tumor antigen 1, Renal tumor antigen |
Target Sequences: | NM_014226 NP_055041.1 Q9UQ07 |
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