Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Gene Name: | matrix metallopeptidase 7 (matrilysin, uterine) |
Family/Subfamily: | Protease , Metallopeptidase M10A |
Synonyms: | MMP7, Matrilysin, Matrin, MMP-7, MPSL1, PUMP-1, Pump-1 protease, MPMM, Uterine matrilysin, Punctuated metalloproteinase 1, Matrix metalloproteinase-7, PUMP1, Uterine metalloproteinase |
Target Sequences: | NM_002423 NP_002414.1 P09237 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.