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MMP3

matrix metallopeptidase 3 (stromelysin 1, progelatinase)

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Gene Name: matrix metallopeptidase 3 (stromelysin 1, progelatinase)
Family/Subfamily: Protease , Metallopeptidase M10A
Synonyms: MMP3, CHDS6, MMP-3, Prostromelysin-1, Proteoglycanase, SL-1, STR1, Matrix metalloproteinase-3, Transin, Transin-1, SLN-1, STMY, Progelatinase, STMY1, Stromelysin-1
Target Sequences: NM_002422 NP_002413.1 P08254

Publications (1)

1
Matrix metalloproteinases are possible mediators for the development of alimentary tract mucositis in the dark agouti rat. Al-Dasooqi N, Gibson RJ, Bowen JM, Logan RM, Stringer AM, Keefe DM. Experimental biology and medicine (Maywood, N.J.). 2010 235:1244-56. (IHC) [PubMed:20682600]

☰ Filters
Products
Proteins (21)
Over-Expression Lysate (2)
Recombinant (19)
MMP3 (21)
No (21)
6His, C-terminus (1)
GST (1)
GST, N-terminus (1)
His (3)
His, N-Terminal (1)
His,C-terminus (1)
His-S (1)
His-SUMO (1)
His-T7 (4)
His-T7, N-terminus (1)
Myc-DDK (Flag) (3)
Cow (1)
Human (14)
Mouse (2)
Pig (1)
Rat (2)
293T Cells (1)
E. coli (13)
HEK 293 Cells (3)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (2)
Purified (5)
Low endotoxin level (4)
Biologically active (1)
MMP3 Protein - Recombinant Matrix Metalloproteinase 3 By SDS-PAGE
Select
E. coli
His
21.4 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
MMP3 Protein - Recombinant Matrix Metalloproteinase 3 By SDS-PAGE
Select
E. coli
His, N-Terminal
17.7 kDa
10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198
MMP3 Protein - Recombinant Matrix Metalloproteinase 3 By SDS-PAGE
Select
E. coli
His-T7
46.5 kDa
10 µg/$284; 50 µg/$460; 100 µg/$735; 200 µg/$917; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225
MMP3 Protein - Recombinant Matrix Metalloproteinase 3 By SDS-PAGE
Select
E. coli
His-T7
46.4 kDa
50 µg/$402; 10 µg/$275; 200 µg/$802; 100 µg/$642; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
MMP3 Protein - Recombinant Matrix Metalloproteinase 3 (MMP3) by SDS-PAGE
Select
E. coli
His-T7, N-terminus
56.3kDa
10 µg/$289; 50 µg/$490; 200 µg/$977; 100 µg/$782; 1 mg/$2,114; 500 µg/$1,640; 5 mg/$3,417; 2 mg/$2,304
MMP3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
53.98 kDa
100 µg/$494
Select
E. coli
His-SUMO
58.5 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
MMP3 Protein
Select
E. coli
His
46.3 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
MMP3 Protein - 12.5% SDS-PAGE of human MMP3 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
80.4 kDa
10 µg/$479; 25 µg/$670
MMP3 Protein
Select
E. coli
His
20 µg/$361; 100 µg/$739; 4 µg/$261
MMP3 Protein - Recombinant  Matrix Metalloproteinase 3 By SDS-PAGE
Select
E. coli
His-S
56 kDa
10 µg/$290; 50 µg/$500; 100 µg/$797; 200 µg/$997; 1 mg/$2,139; 500 µg/$1,662; 5 mg/$3,487; 2 mg/$2,329
MMP3 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
MMP3 Protein - Purified recombinant protein MMP3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
52.2 kDa
20 µg/$1,107
MMP3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
53.98 kDa
20 µg/$150
Select
E. coli
None
29 kDa
20 µg/$502
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
42.8 kDa
2 µg/$268; 10 µg/$349
MMP3 Protein
Select
HEK 293 Cells
None
Less than 1 EU/µg (determined by LAL method).
Predicted molecular mass of approximately 54 kD. The protein migrates at about 55 kD in DTT-reducing conditions and about 60 kD in non-reducing condition by SDS-PAGE. The N-terminal amino acid is Histidine.
10 µg/$355; 25 µg/$497; 100 µg/$1,186
Select
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
53.26 kDa
10 µg/$344; 50 µg/$584
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
53.26kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
MMP3 Protein - Recombinant Matrix Metalloproteinase 3 By SDS-PAGE
Select
E. coli
His-T7
22.9 kDa
10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198
MMP3 Protein - Recombinant Matrix Metalloproteinase 3 By SDS-PAGE
Select
E. coli
His-T7
17.2 kDa
10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198
Viewing 1-21 of 21 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).