MMP12

matrix metallopeptidase 12 (macrophage elastase)

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. It is thought that the protein encoded by this gene is cleaved at both ends to yield the active enzyme, but this processing has not been fully described. The enzyme degrades soluble and insoluble elastin. It may play a role in aneurysm formation and studies in mice suggest a role in the development of emphysema. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

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Proteins (13)

Type

Recombinant (13)

Target

MMP12 (13)

Publications

No (13)

Tag

6His, C-terminus (2)

GST (1)

GST, N-terminus (1)

His (7)

His, N-Terminal (1)

Species

Human (5)

Mouse (3)

Rabbit (1)

Rat (4)

Source

E. coli (9)

Human Cells (1)

Mammalian Cells (1)

Wheat Germ Extract (2)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (2)

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Rat MMP12 Protein (Recombinant His, N-Terminal) (aa100-286) - LS-G12123

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

22.8 kDa

Price:

10 µg/$294; 50 µg/$522; 100 µg/$832; 200 µg/$1,034; 1 mg/$2,192; 500 µg/$1,712; 5 mg/$3,641; 2 mg/$2,383

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Human MMP12 Protein (Recombinant His) (aa106-470) - LS-G20968

Source:

E. coli

Tag:

His

Molecular Weight:

45.9 kD

Price:

100 µg/$420; 1 mg/$1,355; 20 µg/$323

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Mouse MMP12 Protein (Recombinant His) (aa294-473) - LS-G12122

Source:

E. coli

Tag:

His

Molecular Weight:

22.9 kDa

Price:

10 µg/$294; 50 µg/$522; 100 µg/$832; 200 µg/$1,034; 1 mg/$2,192; 500 µg/$1,712; 5 mg/$3,641; 2 mg/$2,383

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Rat MMP12 Protein (Recombinant His) (aa270-362) - LS-G12126

Source:

E. coli

Tag:

His

Molecular Weight:

12.2 kDa

Price:

10 µg/$294; 50 µg/$522; 100 µg/$832; 200 µg/$1,034; 1 mg/$2,192; 500 µg/$1,712; 5 mg/$3,641; 2 mg/$2,383

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Human MMP12 Protein (Recombinant His) (aa290-469) - LS-G12120

Source:

E. coli

Tag:

His

Molecular Weight:

23.2 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284

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Human MMP12 Protein (Recombinant) (Gly106-Asn268) - LS-G138301

Source:

E. coli

Tag:

None

Molecular Weight:

18.2 kDa

Price:

20 µg/$443; 100 µg/$843

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Human MMP12 Protein (Recombinant GST) (Full Length) - LS-G29355

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

80.4 kDa

Price:

2 µg/$439

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Human MMP12 Protein (Recombinant GST, N-terminus) (aa292-401) - LS-G59260

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Mouse MMP12 Protein (Recombinant 6His, C-terminus) (Ala29-Cys473) - LS-G140642

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

53 kDa

Price:

10 µg/$344; 50 µg/$584

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Mouse MMP12 Protein (Recombinant 6His, C-terminus) (Ala29-Cys473) - LS-G39133

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

53kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,353

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Rat MMP12 Protein (Recombinant His) (aa20-99) - LS-G12124

Source:

E. coli

Tag:

His

Molecular Weight:

10.5 kDa

Price:

10 µg/$294; 50 µg/$522; 100 µg/$832; 200 µg/$1,034; 1 mg/$2,192; 500 µg/$1,712; 5 mg/$3,641; 2 mg/$2,383

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Rabbit MMP12 Protein (Recombinant His) (aa286-464) - LS-G12129

Source:

E. coli

Tag:

His

Molecular Weight:

22.8 kDa

Price:

10 µg/$295; 50 µg/$532; 100 µg/$850; 200 µg/$1,049; 1 mg/$2,215; 500 µg/$1,733; 5 mg/$3,711; 2 mg/$2,407

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Rat MMP12 Protein (Recombinant His) (aa372-463) - LS-G12145

Source:

E. coli

Tag:

His

Molecular Weight:

12.6 kDa

Price:

10 µg/$294; 50 µg/$522; 100 µg/$832; 200 µg/$1,034; 1 mg/$2,192; 500 µg/$1,712; 5 mg/$3,641; 2 mg/$2,383

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