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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Unfortunately, the antibody (ID:12325) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



MME / CD10

membrane metallo-endopeptidase

MME / CD10 is a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing.

Gene Name: membrane metallo-endopeptidase
Family/Subfamily: Protease , Metallopeptidase M13
Synonyms: MME, Atriopeptidase, CALLA, CD10, EPN, Membrane metallo-endopeptidase, NEP, Neprilysin, Neutral endopeptidase, Neutral endopeptidase 24.11, CD10 antigen, Enkephalinase, Neprylisin, SFE, Skin fibroblast elastase
Target Sequences: NM_000902 NP_000893.2 P08473

Publications (1)

1
A distinct subset of proinflammatory neutrophils isolated from patients with systemic lupus erythematosus induces vascular damage and synthesizes type I IFNs. Denny MF, Yalavarthi S, Zhao W, Thacker SG, Anderson M, Sandy AR, McCune WJ, Kaplan MJ. Journal of immunology (Baltimore, Md. : 1950). 2010 184:3284-97. [PubMed:20164424] [PMC:PMC2929645] Related Antibodies: LS-C41007.

Filtered By: None
Target
mme-cd10 (191)
Reactivity
Human (160)
Mouse (52)
Rat (48)
Baboon (2)
Bat (4)
Bovine (4)
Chimpanzee (3)
Cynomolgus (1)
Dog (4)
Gibbon (3)
Horse (4)
Monkey (6)
Orangutan (3)
Pig (4)
Rabbit (4)
Rhesus monkey (1)
Application
IHC (107)
IHC-Fr (14)
IHC-P (20)
WB (126)
Flo (73)
ELISA (28)
ICC (2)
IF (11)
IP (28)
Host
rabbit (96)
mouse (95)
Isotype
IgG (74)
IgG1 (62)
IgG1,k (12)
IgG2a (1)
IgG2b (11)
IgG2b,k (2)
IgM (1)
IgM,k (1)
Clonality
monoclonal mc (94)
polyclonal pc (97)
Clone
2A1H5E1 (1)
3D11 (1)
3G6B11 (1)
56C6 (6)
5B8 (1)
5E9A5 (1)
6G12E12 (1)
7D4B1 (1)
B396 (1)
CB-CALLA (12)
E19-P (1)
FR4D11 (2)
G27-P (1)
HI10a (3)
LT10 (3)
MEM-78 (9)
RXB.14 (2)
SN5c/L4-1A1 (9)
SS2/36 (1)
Format
AP Conjugated (6)
APC (5)
APC Conjugated (12)
Azide-free (7)
Biotin Conjugated (19)
Cy3 Conjugated (5)
Cy5 Conjugated (2)
Cy7 Conjugated (6)
DY594 Conjugated (1)
FITC Conjugated (24)
HRP Conjugated (12)
PE (4)
PE Conjugated (19)
PerCP Conjugated (1)
Ready-to-Use (1)
RPE Conjugated (1)
Unconjugated (83)
Epitope
aa455-750 (10)
aa32-164 (9)
aa382-538 (9)
aa286-428 (8)
aa506-534 (8)
aa565-750 (8)
aa721-747 (8)
C-Terminus (4)
aa492-525 (3)
aa99-132 (3)
aa272-300 (2)
aa52-246 (2)
aa52-750 (2)
Internal (1)
N-Terminus (1)
aa274-302 (1)
aa297-483 (1)
aa491-540 (1)
aa6-10 (1)
Publications
No (190)
Yes (1)
Showing 1-25 of 191 results

MME / CD10 Antibody (aa274-302) IHC-plus™ LS-B11799
Rabbit Polyclonal to Human MME / CD10
Mouse, Human
IF IHC IHC-P WB
Unconjugated
200µl  $425.00
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

MME / CD10 Antibody (clone MEM-78, Biotin) LS-C46270
Mouse Monoclonal [clone MEM-78] (IgG1) to Human MME / CD10
Human
Flo IF
Biotin Conjugated
100µg 1mg/ml  $290.00

MME / CD10 Antibody (clone HI10a) LS-C41007
Publications (1)
Publications (1)
Mouse Monoclonal [clone HI10a] (IgG1) to Human MME / CD10
Human, Monkey, Baboon
Flo
Unconjugated
100µg  $225.00
Nalm-6 cell line stained with purified HI10a and detected with anti-mouse IgGs-FITC
Nalm-6 cell line stained with purified HI10a and detected with anti-mouse IgGs-FITC

MME / CD10 Antibody LS-C43729
Mouse Monoclonal (IgG1) to Human MME / CD10
Human
Flo IHC IHC-Fr IP WB
Unconjugated
100µg 1mg/ml  $265.00

MME / CD10 Antibody LS-C12759
Mouse Monoclonal (IgG1) to Human MME / CD10
Human
IHC IHC-Fr IHC-P WB
Unconjugated
250µl  $335.00; 500µl  $740.00; 1000µl  $1,335.00

MME / CD10 Antibody (clone E19-P) IHC-plus™ LS-B9955
Rabbit Polyclonal [clone E19-P] to Human MME / CD10
IHC IHC-P
Unconjugated
100µl  $425.00
Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

MME / CD10 Antibody (clone 56C6) IHC-plus™ LS-B5173
Mouse Monoclonal [clone 56C6] (IgG1) to Human MME / CD10
Rat, Human
IHC IHC-P
Unconjugated
125µl  $425.00
Anti-CD10 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5173 dilution 1:50.
Anti-CD10 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5173 dilution 1:50.

MME / CD10 Antibody (clone 56C6) IHC-plus™ LS-B14553
Mouse Monoclonal [clone 56C6] (IgG1) to Human MME / CD10
Human
IHC IHC-Fr IHC-P
Unconjugated
100µl  $425.00
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)

MME / CD10 Antibody (clone 2A1H5E1) LS-C47144
Mouse Monoclonal [clone 2A1H5E1] (IgG2b) to Human MME / CD10
Human
ELISA IHC
Unconjugated
100µg 1mg/ml  $315.00
Immunohistochemistry Image
Immunohistochemistry Image

MME / CD10 Antibody (clone SS2/36) LS-C170888
Mouse Monoclonal [clone SS2/36] (IgG1,k) to Human MME / CD10
Human
IHC IHC-Fr
Unconjugated
500µl  $225.00

MME / CD10 Antibody (Biotin) LS-C35423
Mouse Monoclonal (IgG1,k) to Human MME / CD10
Human
Flo WB
Biotin Conjugated
100µg 1mg/ml  $495.00

MME / CD10 Antibody LS-C16784
Rabbit Polyclonal (IgG) to Rat MME / CD10
Mouse, Rat, Human
IHC WB
Unconjugated
50µl  $650.00

MME / CD10 Antibody (aa272-300) LS-C164229
Mouse Monoclonal (IgM,k) to Human MME / CD10
Human
WB
Unconjugated
400µl  $305.00
MME/CD10 western blot of CEM cell line lysates (35 ug/lane). The MME/CD10 antibody detected the MME/CD10 protein (arrow).
MME/CD10 western blot of CEM cell line lysates (35 ug/lane). The MME/CD10 antibody detected the MME/CD10 protein (arrow).

MME / CD10 Antibody (clone CB-CALLA, PE) LS-C107140
Mouse Monoclonal [clone CB-CALLA] (IgG2b) to Human MME / CD10
Human
Flo
PE Conjugated
25tst  $225.00; 100tst  $345.00
Staining of normal human peripheral blood cells with PE Mouse IgG2b isotype control (open histogram) or PE anti-human CD10 (CB-CALLA) (colored histogram). Cells in the granulocyte gate were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Staining of normal human peripheral blood cells with PE Mouse IgG2b isotype control (open histogram) or PE anti-human CD10 (CB-CALLA) (colored histogram). Cells in the granulocyte gate were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.

MME / CD10 Antibody (C-Terminus) LS-C146479
Rabbit Polyclonal to Human MME / CD10
Rabbit, Dog, Bovine, Pig, Horse, Bat, Human, Monkey
WB
Unconjugated
50µg  $365.00
MME / CD10 antibody LS-C146479 Western blot of 3 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
MME / CD10 antibody LS-C146479 Western blot of 3 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

MME / CD10 Antibody (aa6-10) LS-C205131
Rabbit Polyclonal to Human MME / CD10
Mouse, Rat, Human
WB
Unconjugated
50µg 50µl 1mg/ml  $295.00; 100µg 100µl 1mg/ml  $355.00
Western blot of extract from Rat kidney tissue using CD10 antibody
Western blot of extract from Rat kidney tissue using CD10 antibody

MME / CD10 Antibody LS-C12766
Mouse Monoclonal (IgG1) to Human MME / CD10
Human
Flo IF IHC IHC-Fr
Unconjugated
100µg  $405.00

MME / CD10 Antibody (clone G27-P) IHC-plus™ LS-B10194
Rabbit Polyclonal [clone G27-P] to Human MME / CD10
Human
IHC IHC-Fr IHC-P
Unconjugated
50µl  $425.00
Anti-MME / CD10 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-MME / CD10 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

MME / CD10 Antibody (clone 3G6B11) LS-C682584
Mouse Monoclonal [clone 3G6B11] (IgG1) to Human MME / CD10
Human
ELISA Flo IHC WB
Unconjugated
100µl  $365.00

MME / CD10 Antibody (clone MEM-78) LS-C202017
Mouse Monoclonal [clone MEM-78] (IgG1) to Human MME / CD10
Human
Flo IF IP WB
Unconjugated
100µg 1mg/ml  $455.00

MME / CD10 Antibody (aa506-534) LS-C164829
Rabbit Polyclonal to Human MME / CD10
Human
Flo IHC IHC-P WB
Unconjugated
400µl  $305.00
Formalin-fixed and paraffin-embedded human kidney carcinoma with Neprilysin Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Western blot of Neprilysin Antibody in A2058,A375,Ramos cell line lysates (35 ug/lane). EPN (arrow) was detected using the purified antibody.
Formalin-fixed and paraffin-embedded human kidney carcinoma with Neprilysin Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Western blot of Neprilysin Antibody in A2058,A375,Ramos cell line lysates (35 ug/lane). EPN (arrow) was detected using the purified antibody.

MME / CD10 Antibody (clone MEM-78) LS-C40995
Mouse Monoclonal [clone MEM-78] (IgG1) to Human MME / CD10
Human
Flo IHC IHC-Fr IP WB
Unconjugated
100µg 0.5mg/ml  $225.00

MME / CD10 Antibody (Azide-free) LS-C43731
Mouse Monoclonal (IgG1) to Human MME / CD10
Human
Flo IHC IHC-Fr IP WB
Unconjugated, Azide-free
1000µg 1mg/ml  $830.00

MME / CD10 Antibody LS-C122905
Mouse Monoclonal (IgG1) to Human MME / CD10
Human
Flo IHC IHC-Fr IHC-P IP WB
Unconjugated
100µg  $415.00

MME / CD10 Antibody LS-C12758
Mouse Monoclonal (IgG1) to Human MME / CD10
Human
Flo IHC IHC-Fr IP WB
Unconjugated
100µg  $425.00
Showing 1-25 of 191 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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