MME / CD10

membrane metallo-endopeptidase

MME / CD10 is a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing.

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Products

Proteins (33)

Type

Over-Expression Lysate (14)

Recombinant (19)

Target

MME / CD10 (33)

Application

SDS-PAGE (1)

Publications

No (33)

Tag

Fc (1)

GST (1)

GST, N-terminus (1)

His (6)

His, N-Terminal (1)

His,N-terminus (1)

His-GST (2)

Myc-DDK (Flag) (18)

Species

Human (22)

Mouse (1)

Rat (3)

Source

293T Cells (7)

E. coli (5)

HEK 293 Cells (13)

Human (1)

Human Cells (3)

Mammalian Cells (1)

Wheat Germ Extract (2)

Yeast (1)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (7)

Biologically Active

Biologically active (1)

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Human MME / CD10 Protein (Recombinant) (Tyr52-Trp750) - LS-G48400

Source:

HEK 293 Cells

Tag:

None

Application:

SDS-PAGE

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant human MME consists of 699 amino acids and predicts a molecular mass of 80 kDa. As a result of glycosylation, rhMME migrates as approximately 90-100 kDa band in SDS-PAGE under reducing conditions.

Price:

50 µg/$441

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Human MME / CD10 Protein (Recombinant His) (aa52-750) - LS-G23026

Source:

Yeast

Tag:

His

Molecular Weight:

81.83 kD

Price:

100 µg/$446; 20 µg/$336; 1 mg/$1,460

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MME / CD10 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123471

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

85.3 kDa

Price:

100 µg/$710

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MME / CD10 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G127019

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

85.3 kDa

Price:

100 µg/$710

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MME / CD10 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G127020

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

85.3 kDa

Price:

100 µg/$710

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MME / CD10 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G114728

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

85.3 kDa

Price:

100 µg/$710

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MME / CD10 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G114730

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

85.3 kDa

Price:

100 µg/$494

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MME / CD10 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G114733

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

85.3 kDa

Price:

100 µg/$710

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Human MME / CD10 Protein (Recombinant GST) (Full Length) - LS-G29347

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

111.9 kDa

Price:

10 µg/$479; 25 µg/$670

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Mouse MME / CD10 Protein (Recombinant His-GST) (aa455-750) - LS-G24486

Source:

E. coli

Tag:

His-GST

Molecular Weight:

63.9 kDa

Price:

10 µg/$285; 50 µg/$470; 100 µg/$750; 200 µg/$937; 1 mg/$2,063; 500 µg/$1,594; 5 mg/$3,277; 2 mg/$2,252

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Human MME / CD10 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66404

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

85.3 kDa

Price:

20 µg/$1,107

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Human MME / CD10 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66405

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

85.3 kDa

Price:

20 µg/$1,107

Select

Human MME / CD10 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66406

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

85.3 kDa

Price:

20 µg/$1,107

Select

Human MME / CD10 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66407

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

85.3 kDa

Price:

20 µg/$1,107

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Human MME / CD10 Protein (Recombinant GST, N-terminus) (aa145-250) - LS-G59254

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human MME / CD10 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77624

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

85.3 kDa

Price:

20 µg/$215

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Human MME / CD10 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77623

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

85.3 kDa

Price:

20 µg/$215

Select

Human MME / CD10 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77625

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

85.3 kDa

Price:

20 µg/$215

Select

Human MME / CD10 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77626

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

85.3 kDa

Price:

20 µg/$215

Select

Human MME / CD10 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77628

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

85.3 kDa

Price:

20 µg/$215

Select

Human MME / CD10 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77627

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

85.3 kDa

Price:

20 µg/$150

Select

Human MME / CD10 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77630

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

85.3 kDa

Price:

20 µg/$215

Select

MME / CD10 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99211

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

85.3 kDa

Price:

100 µg/$710

Select

Human MME / CD10 Protein (Recombinant) (Tyr52-Trp750) - LS-G138432

Source:

HEK 293 Cells

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

80 kDa

Price:

50 µg/$854

Select

Human MME / CD10 Protein (Recombinant His,N-terminus) (Tyr52-Trp750) - LS-G140546

Source:

Mammalian Cells

Tag:

His,N-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

80.9 kDa

Price:

10 µg/$344; 50 µg/$584

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