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MMD2 encodes a member of the PAQR (progestin and adipoQ receptor) family. Members of this family are evolutionarily conserved with significant sequence identity to bacterial hemolysin-like proteins and are defined by a set of seven transmembrane domains. The protein encoded by this gene localizes to the Golgi apparatus to modulate Ras signaling. Alternative splicing results in multiple transcript variants and protein isoforms.
Gene Name: | monocyte to macrophage differentiation-associated 2 |
Synonyms: | MMD2, PAQR10 |
Target Sequences: | Q8IY49 Q8IY49 |
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