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MLLT3 / AF9

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3

Component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA.

Gene Name: myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
Synonyms: MLLT3, AF-9, AF9, Protein AF-9, Translocated to, 3, YEATS3
Target Sequences: NM_004529 NP_004520.2 P42568

Publications (1)

1
The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling. Bitoun E, Oliver PL, Davies KE. Human molecular genetics. 2007 16:92-106. [PubMed:17135274] Related Antibodies: LS-C100430.

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
MLLT3 / AF9 (5)
No (5)
6His-B2M, N-terminus (1)
GST (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (2)
MLLT3 / AF9 Protein - 12.5% SDS-PAGE of human MLLT3 stained with Coomassie Blue
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Wheat Germ Extract
GST
88 kDa
2 µg/$439
MLLT3 / AF9 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
63.2 kDa
20 µg/$150
MLLT3 / AF9 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His-B2M, N-terminus
100 µg/$1,128; 20 µg/$721
MLLT3 / AF9 Protein - Purified recombinant protein MLLT3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
63.2 kDa
20 µg/$1,107
MLLT3 / AF9 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
63.2 kDa
100 µg/$494
Viewing 1-5 of 5 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).