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Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). Reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. Involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation. May play a role in the regulation of terminal myogenesis.
Gene Name: | nicotinamide riboside kinase 2 |
Synonyms: | NMRK2, NRK2, Nicotinamide riboside kinase 2, ITGB1BP3, RNK 2, MIBP, NmR-K 2, NRK 2, Ribosylnicotinamide kinase 2, Ribosylnicotinic acid kinase 2 |
Target Sequences: | NM_014446 NP_733778.1 Q9NPI5 |
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