order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Locations
Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
Contact Us
Additional Contact Details
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Forgot password?
order histories, retained contact details for faster checkout, review submissions, and special promotions.
MIB1
mindbomb E3 ubiquitin protein ligase 1
E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. Probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis By similarity. Involved in ubiquitination of centriolar satellite CEP131, CEP290 and PCM1 proteins and hence inhibits primary cilium formation in proliferating cells. Mediates 'Lys-63'-linked polyubiquitination of TBK1, which probably participates in kinase activation.
| Gene Name: | mindbomb E3 ubiquitin protein ligase 1 |
| Synonyms: | MIB1, DIP-1, DIP1, Mindbomb homolog 1, KIAA1323, Mind bomb homolog 1, Ubiquitin ligase protein MIB1, Ubiquitin ligase mind bomb, ZZZ6, DAPK-interacting protein 1, Mib, ZZANK2 |
| Target Sequences: | AB037744 BAA92561.1 Q86YT6 |
Publications (1)
Your search did not match any products.
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
