MGME1 / C20orf72

mitochondrial genome maintenance exonuclease 1

Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity but is also capable of endoduclease activity on linear substrates. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair, possibly via the processing of displaced DNA containing Okazaki fragments during RNA-primed DNA synthesis on the lagging strand or via processing of DNA flaps during long-patch base excision repair. Specifically binds 5-hydroxymethylcytosine (5hmC)-containing DNA in stem cells.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

MGME1 / C20orf72 (3)

Publications

No (3)

Tag

Myc-DDK (Flag) (3)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (2)

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Human MGME1 / C20orf72 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G73309

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.2 kDa

Price:

20 µg/$1,107

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Human MGME1 / C20orf72 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G94905

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.2 kDa

Price:

20 µg/$150

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MGME1 / C20orf72 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102146

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.2 kDa

Price:

100 µg/$494

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