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Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN1 acts independently of the cytoskeleton. Overexpression induces the formation of mitochondrial networks.
Gene Name: | mitofusin 1 |
Synonyms: | MFN1, Fzo homolog, Hfzo2, Mitofusin-1, Hfzo1, Mitofusin 1, Putative transmembrane GTPase, Transmembrane GTPase MFN1 |
Target Sequences: | NM_033540 NP_284941.2 Q8IWA4 |
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