MEP1B

meprin A, beta

Meprins are multidomain zinc metalloproteases that are highly expressed in mammalian kidney and intestinal brush border membranes, and in leukocytes and certain cancer cells. They are involved in the hydrolysis of a variety of peptide and protein substrates, and have been implicated in cancer and intestinal inflammation. Mature meprins are oligomers of evolutionarily related, but separately encoded alpha and/or beta subunits. Homooligomers of alpha subunit are secreted, whereas, oligomers containing the beta subunit are plasma membrane-bound. This gene encodes the beta subunit. Targeted disruption of this gene in mice affects embryonic viability, renal gene expression profiles, and distribution of the membrane-associated alpha subunit in kidney and intestine.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

MEP1B (3)

Publications

No (3)

Tag

His-T7 (1)

Myc-DDK (Flag) (2)

Species

Human (1)

Rat (1)

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293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

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MEP1B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115642

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

79.4 kDa

Price:

100 µg/$710

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Rat MEP1B Protein (Recombinant His-T7) (aa433-679) - LS-G11726

Source:

E. coli

Tag:

His-T7

Molecular Weight:

31.4 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284

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Human MEP1B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77315

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

79.4 kDa

Price:

20 µg/$215

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