MEN1 / Menin

multiple endocrine neoplasia I

Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair.

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Products

Proteins (9)

Type

Over-Expression Lysate (4)

Recombinant (5)

Target

MEN1 / Menin (9)

Publications

No (9)

Tag

GST (2)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (5)

Species

Human (7)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (3)

Wheat Germ Extract (3)

Purification

Purified (2)

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Human MEN1 / Menin Protein (Recombinant His) (aa219-395) - LS-G24711

Source:

E. coli

Tag:

His

Molecular Weight:

24.3 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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MEN1 / Menin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G107659

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

67.3 kDa

Price:

100 µg/$710

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MEN1 / Menin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G107662

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

67.8 kDa

Price:

100 µg/$710

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Human MEN1 / Menin Protein (Recombinant GST) (Full Length) - LS-G29311

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

88.88 kDa

Price:

2 µg/$439

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Human MEN1 / Menin Protein (Recombinant GST) (Full Length) - LS-G29312

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

90.1 kDa

Price:

10 µg/$479; 25 µg/$670

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Human MEN1 / Menin Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68338

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

67.3 kDa

Price:

20 µg/$1,107

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Human MEN1 / Menin Protein (Recombinant GST, N-terminus) (aa506-615) - LS-G59223

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human MEN1 / Menin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81957

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

67.3 kDa

Price:

20 µg/$215

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Human MEN1 / Menin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81958

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

67.8 kDa

Price:

20 µg/$215

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