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MED12

mediator complex subunit 12

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.

Gene Name: mediator complex subunit 12
Synonyms: MED12, ARC240, CAG repeat protein 45, CAGH45, FG syndrome 1, Hypothetical protein kiaa0192, FGS1, Mediator complex subunit 12, Putative mediator subunit 12, MED12S, TNRC11, TRAP230, HOPA, Human opposite paired, KIAA0192, OKS, OPA-containing protein
Target Sequences: NM_005120 NP_005111.2 Q93074

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Proteins (1)
Recombinant (1)
MED12 (1)
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GST, N-terminus (1)
Human (1)
Wheat Germ Extract (1)
MED12 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).