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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
Malic enzyme catalyzes the oxidative decarboxylation of malate to pyruvate using either NAD+ or NADP+ as a cofactor. Mammalian tissues contain 3 distinct isoforms of malic enzyme: a cytosolic NADP(+)-dependent isoform, a mitochondrial NADP(+)-dependent isoform, and a mitochondrial NAD(+)-dependent isoform. This gene encodes a mitochondrial NADP(+)-dependent isoform. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.
| Gene Name: | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| Synonyms: | ME3, Malate dehydrogenase, NADP-ME, Pyruvic-malic carboxylase, Malic enzyme 3 |
| Target Sequences: | NM_006680 NP_006671.2 Q16798 |
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