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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ME2 / Malate Dehydrogenase 2

malic enzyme 2, NAD(+)-dependent, mitochondrial

ME2 / Malate Dehydrogenase 2 encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.

Gene Name: malic enzyme 2, NAD(+)-dependent, mitochondrial
Synonyms: ME2, Malate dehydrogenase, Pyruvic-malic carboxylase, Malic enzyme 2, NAD-ME, ODS1
Target Sequences: NM_002396 NP_002387.1 P23368

Filtered by: None
Target
ME2 / Malate Dehydrogenase 2 (33)
Reactivity
Human (33)
Mouse (16)
Rat (4)
Bovine (4)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Hamster (4)
Monkey (4)
Rabbit (4)
Application
IHC (12)
IHC-P (5)
WB (29)
ELISA (16)
IF (2)
Peptide-ELISA (1)
Host
rabbit (32)
mouse (1)
Isotype
IgG (22)
IgG1,k (1)
Clonality
monoclonal mc (1)
polyclonal pc (32)
Clone
970CT2.1.1.2 (1)
Format
AP Conjugated (1)
APC (1)
APC Conjugated (2)
Azide-free (1)
Biotin Conjugated (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (14)
Epitope
aa220-426 (8)
aa527-556 (8)
aa38-87 (4)
180-260 aa, Internal (1)
C-Terminus (1)
aa201-250 (1)
Publications
No (33)
Showing 1-25 of 33 results

IHC-plus™ ME2 / Malate Dehydrogenase 2 Antibody LS-B12050
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05mg 1mg/ml  $425.00
Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)

ME2 / Malate Dehydrogenase 2 Antibody (aa201-250) LS-C199244
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Immunohistochemistry analysis of paraffin-embedded human placenta tissue, using ME2 Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from RAW264.7 and LOVO cells, using ME2 Antibody. The lane on the right is blocked with the synthesized peptide.

ME2 / Malate Dehydrogenase 2 Antibody (aa527-556) LS-C329825
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Mouse, Human
ELISA, IHC, WB
Unconjugated
200µl  $590.00

ME2 / Malate Dehydrogenase 2 Antibody (aa527-556, Biotin) LS-C262889
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200µl  $740.00

ME2 / Malate Dehydrogenase 2 Antibody (aa527-556, FITC) LS-C262890
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200µl  $740.00

ME2 / Malate Dehydrogenase 2 Antibody (aa527-556, APC) LS-C262888
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200µl  $740.00

ME2 / Malate Dehydrogenase 2 Antibody (aa527-556, Azide-free, HRP) LS-C262891
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200µl  $740.00

ME2 / Malate Dehydrogenase 2 Antibody (aa527-556, AP) LS-C262886
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Mouse, Human
ELISA, IHC, WB
AP Conjugated
200µl  $740.00

ME2 / Malate Dehydrogenase 2 Antibody (aa527-556, PE) LS-C262892
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200µl  $740.00

ME2 / Malate Dehydrogenase 2 Antibody (180-260 aa, Internal) LS-C384470
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Human
ELISA, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00

ME2 / Malate Dehydrogenase 2 Antibody LS-C808703
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Mouse, Human
ELISA, IF, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunofluorescence Image
Western blot Image

ME2 / Malate Dehydrogenase 2 Antibody LS-C678607
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Human
ELISA, IHC, IHC-P
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human endometrial cancer at dilution of 1:100

ME2 / Malate Dehydrogenase 2 Antibody (HRP) LS-C678610
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Human
ELISA
HRP Conjugated
50µg  $285.00; 100µg  $385.00

ME2 / Malate Dehydrogenase 2 Antibody (Biotin) LS-C678608
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Human
ELISA
Biotin Conjugated
50µg  $285.00; 100µg  $385.00

ME2 / Malate Dehydrogenase 2 Antibody (FITC) LS-C678609
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Human
ELISA
FITC Conjugated
50µg  $285.00; 100µg  $385.00

ME2 / Malate Dehydrogenase 2 Antibody (aa527-556) LS-C164112
Rabbit Polyclonal to Human ME2 / Malate Dehydrogenase 2
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400µl  $325.00
ME2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human rectum tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
ME2 Antibody western blot of mouse NIH-3T3,Neuro-2a cell line lysates (35 ug/lane). The ME2 antibody detected the ME2 protein (arrow).

ME2 / Malate Dehydrogenase 2 Antibody (C-Terminus, clone 970CT2.1.1.2) LS-C757799
Mouse Monoclonal [clone 970CT2.1.1.2] (IgG1,k) to Human ME2 / Malate Dehydrogenase 2
Mouse, Human
ELISA, IHC-P, WB
Unconjugated
200µl  $325.00
ME2 Antibody (C-term) staining ME2 in human kidney tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with formaldehyde and blocked with 3% BSA for 0. 5 hour at room temperature; antigen retrieval was by heat mediation with a citrate buffer (pH6). Samples were incubated with primary antibody (1/25) for 1 hours at 37°C. A undiluted biotinylated goat polyvalent antibody was used as the secondary antibody.
All lanes: Anti-ME2 Antibody (C-term) at 1:4000 dilution Lane 1: HL-60 whole cell lysate Lane 2: NIH/3T3 whole cell lysate Lane 3: Jurkat whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-mouse IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 65 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

ME2 / Malate Dehydrogenase 2 Antibody LS-C666695
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Human
ELISA, WB
Unconjugated
100µg  $375.00

ME2 / Malate Dehydrogenase 2 Antibody LS-C768103
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Mouse, Human
WB
Unconjugated
60µl 1mg/ml  $235.00; 120µl 1mg/ml  $295.00; 200µl 1mg/ml  $395.00

ME2 / Malate Dehydrogenase 2 Antibody (aa38-87) LS-C81589
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Human, Monkey
WB
Unconjugated
100µl 0.5mg/ml  $385.00
Jurkat cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ME2 / Malate Dehydrogenase 2 Antibody (aa38-87, HRP) LS-C453988
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
WB
HRP Conjugated
100µl 0.65mg/ml  $405.00
Jurkat cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ME2 / Malate Dehydrogenase 2 Antibody (aa38-87, FITC) LS-C453986
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Chimpanzee, Gibbon, Human, Monkey
WB
FITC Conjugated
100µl 1mg/ml  $405.00
Jurkat cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

ME2 / Malate Dehydrogenase 2 Antibody LS-C667894
Rabbit Polyclonal to Human ME2 / Malate Dehydrogenase 2
Human
WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $275.00
Western blot Image

ME2 / Malate Dehydrogenase 2 Antibody LS-C411185
Rabbit Polyclonal (IgG) to Human ME2 / Malate Dehydrogenase 2
Mouse, Human
WB
Unconjugated
50µl  $235.00; 100µl  $295.00; 200µl  $385.00
Western blot analysis of extract of various cells.

ME2 / Malate Dehydrogenase 2 Antibody (aa220-426) LS-C373597
Rabbit Polyclonal to Human ME2 / Malate Dehydrogenase 2
Human
WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $530.00
Western blot of ME2 / Malate Dehydrogenase 2 antibody.
Western Blot; Sample: Lane1: Human Lung Tissue; Lane2: Human Jurkat Cells; Lane3: Human K562 Cells; Lane4: Human Hela Cells.
Showing 1-25 of 33 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).