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MDM1 encodes a nuclear protein similar to the mouse double minute 1 protein. The mouse gene is located in double minute (DM) chromatin particles, is amplified in the mouse transformed 3T3 cell line, and the encoded protein is able to bind to p53. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene Name: | Mdm1 nuclear protein homolog |
Synonyms: | MDM1, Nuclear protein MDM1 |
Target Sequences: | NM_017440 NP_059136.2 Q8TC05 |
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