MDFI / I-MF

myoD family inhibitor

Inhibits the transactivation activity of the Myod family of myogenic factors and represses myogenesis. Acts by associating with Myod family members and retaining them in the cytoplasm by masking their nuclear localization signals. Can also interfere with the DNA-binding activity of Myod family members. Plays an important role in trophoblast and chondrogenic differentiation. Regulates the transcriptional activity of TCF7L1/TCF3 by interacting directly with TCF7L1/TCF3 and preventing it from binding DNA. Binds to the axin complex, resulting in an increase in the level of free beta-catenin. Affects axin regulation of the WNT and JNK signaling pathways.

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Products

Proteins (2)

Type

Recombinant (2)

Target

MDFI / I-MF (2)

Publications

No (2)

Tag

GST (1)

GST, N-terminus (1)

Species

Human (2)

Source

Wheat Germ Extract (2)

Purification

Purified (1)

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Human MDFI / I-MF Protein (Recombinant GST) (Full Length) - LS-G29293

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

51.4 kDa

Price:

10 µg/$479; 25 µg/$670

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Human MDFI / I-MF Protein (Recombinant GST, N-terminus) (aa33-110) - LS-G59204

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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