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MCF2L / DBS

MCF.2 Cell Line Derived Transforming Sequence-like

Guanine nucleotide exchange factor that potentially links pathways that signal through RAC1, RHOA and CDC42. Catalyzes guanine nucleotide exchange on RHOA and CDC42 and interacts specifically with the GTP-bound form of RAC1, suggesting that it functions as an effector of RAC1. May also participate in axonal transport in the brain. Becomes activated and highly tumorigenic by truncation of the N-terminus By similarity. Isoform 5 activates CDC42.

Gene Name: MCF.2 Cell Line Derived Transforming Sequence-like
Synonyms: MCF2L, ARHGEF14, DBS, KIAA0362, OST, DBLs big sister
Target Sequences: NM_024979 NP_079255.4 O15068

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Products
Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
MCF2L / DBS (4)
No (4)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
MCF2L / DBS Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
131.2 kDa
100 µg/$710
MCF2L / DBS Protein - Purified recombinant protein MCF2L was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
126.6 kDa
20 µg/$1,107
MCF2L / DBS Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
MCF2L / DBS Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
131.2 kDa
20 µg/$215
Viewing 1-4 of 4 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).