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MCC

mutated in colorectal cancers

Candidate for the putative colorectal tumor suppressor gene located at 5q21. Suppresses cell proliferation and the Wnt/b-catenin pathway in colorectal cancer cells. Inhibits DNA binding of b-catenin/TCF/LEF transcription factors. Involved in cell migration independently of RAC1, CDC42 and p21-activated kinase (PAK) activation.

Gene Name: mutated in colorectal cancers
Synonyms: MCC, MCC1, Protein MCC, Mutated in colorectal cancers
Target Sequences: nm_002387 NP_002378.1 P23508

☰ Filters
Products
Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
MCC (5)
No (5)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
MCC Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
MCC Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
92.9 kDa
100 µg/$494
MCC Protein - 12.5% SDS-PAGE of human MCC stained with Coomassie Blue
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Wheat Germ Extract
GST
119.5 kDa
10 µg/$479; 25 µg/$670
MCC Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
92.9 kDa
20 µg/$150
MCC Protein - Purified recombinant protein MCC was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
92.9 kDa
20 µg/$1,107
Viewing 1-5 of 5 product results


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Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).