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MC2R / ACTHR / ACTH Receptor
melanocortin 2 receptor (adrenocorticotropic hormone)
MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. Alternate transcript variants have been found for this gene.
| Gene Name: | melanocortin 2 receptor (adrenocorticotropic hormone) |
| Family/Subfamily: | GPCR , Melanocortin |
| Synonyms: | MC2R, ACTHR, ACTH receptor, ACTH-R, Adrenocorticotropic receptor, Adrenocorticotropin receptor, Melanocortin 2 receptor, Melanocortin receptor 2, MC2-R, MC2 receptor |
| Target Sequences: | NM_000529 NP_000520.1 Q01718 |
Publications (2)
1
ACTH treatment promotes murine cardiac allograft acceptance. Jing Zhao , Liwei Jiang , Mayuko Uehara , Naima Banouni , Basmah S Al Dulaijan , Jamil Azzi , Takaharu Ichimura, Xiaofei Li , Petr Jarolim, Paolo Fiorina , Stefan G Tullius, Joren C Madsen , Vivek Kasinath , Reza Abdi. JCI insight. 2021 Jul;6:e143385. [Full Text Article]
[PubMed:34236047]
[PMC:PMC8410061]
Related Antibodies: LS-C164069.
2
Morphologic and Molecular Characterization of Adrenals and Adrenal Rest Affected by Congenital Adrenal Hyperplasia. Vipula Kolli, Isabela Werneck da Cunha, SunA Kim, James R Iben, Ashwini Mallappa, Tianwei Li, Alison Gaynor, Steven L Coon, Martha M Quezado, Deborah P Merke. Frontiers in endocrinology. 2021 October;12:730947. [Full Text Article]
[PubMed:34616364]
[PMC:PMC8488225]
Related Antibodies: LS-C164069.
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Products
Antibodies
(24)
Type
Primary
(24)
Target
MC2R / ACTHR / ACTH Receptor
(24)
Reactivity
Human
(21)
Mouse
(10)
Rat
(4)
Chimpanzee
(3)
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(3)
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IHC
(8)
IHC-P
(1)
WB
(23)
Flo
(2)
ELISA
(11)
IF
(4)
Peptide-ELISA
(4)
Host
rabbit
(22)
goat
(1)
rabbit-new zealand white
(1)
Isotype
IgG
(16)
Clonality
polyclonal pc
(24)
Format
APC Conjugated
(1)
Azide-free
(1)
Biotin Conjugated
(2)
FITC Conjugated
(2)
HRP Conjugated
(2)
PE Conjugated
(1)
Unconjugated
(16)
Epitope
aa261-288
(7)
aa86-135
(4)
220-300 aa, C-terminal
(1)
4th Cytoplasmic Domain
(1)
C-Terminus
(1)
aa240-289
(1)
aa248-297
(1)
aa60-110
(1)
aa9-21
(1)
Publications
No
(23)
Yes
(1)
MC2R / ACTHR / ACTH Receptor Rabbit anti-Human Polyclonal (aa261-288) Antibody
Human
Flo, IHC, IHC-P
Unconjugated
400 µl/$393
MC2R / ACTHR / ACTH Receptor Rabbit anti-Human Polyclonal (aa248-297) Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
MC2R / ACTHR / ACTH Receptor Rabbit anti-Human Polyclonal (aa261-288) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
MC2R / ACTHR / ACTH Receptor Rabbit anti-Human Polyclonal (aa261-288) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
MC2R / ACTHR / ACTH Receptor Rabbit anti-Human Polyclonal (aa261-288) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
MC2R / ACTHR / ACTH Receptor Rabbit anti-Human Polyclonal (aa261-288) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
MC2R / ACTHR / ACTH Receptor Rabbit anti-Human Polyclonal (aa261-288) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
MC2R / ACTHR / ACTH Receptor Rabbit anti-Human Polyclonal (aa261-288) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
MC2R / ACTHR / ACTH Receptor Rabbit anti-Human Polyclonal (220-300 aa, C-terminal) Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
MC2R / ACTHR / ACTH Receptor Rabbit anti-Mouse Polyclonal (4th Cytoplasmic Domain) Antibody
Mouse
ELISA, WB
Unconjugated
50 µg/$797
MC2R / ACTHR / ACTH Receptor Goat anti-Human Polyclonal (aa9-21) Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
MC2R / ACTHR / ACTH Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
MC2R / ACTHR / ACTH Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
MC2R / ACTHR / ACTH Receptor Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$832
MC2R / ACTHR / ACTH Receptor Rabbit-New Zealand White anti-Human Polyclonal (aa60-110) Antibody
Human
IHC, WB
Unconjugated
100 µl/$393
MC2R / ACTHR / ACTH Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
MC2R / ACTHR / ACTH Receptor Rabbit anti-Human Polyclonal (aa240-289) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
MC2R / ACTHR / ACTH Receptor Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat
WB
Unconjugated
100 µg/$575
MC2R / ACTHR / ACTH Receptor Rabbit anti-Human Polyclonal (aa86-135) Antibody
Human
WB
Unconjugated
100 µl/$424
MC2R / ACTHR / ACTH Receptor Rabbit anti-Human Polyclonal (aa86-135) (HRP) Antibody
Rat, Chimpanzee, Gibbon, Human
WB
HRP Conjugated
100 µl/$469
MC2R / ACTHR / ACTH Receptor Rabbit anti-Human Polyclonal (aa86-135) (Biotin) Antibody
Rat, Chimpanzee, Gibbon, Human
WB
Biotin Conjugated
100 µl/$469
MC2R / ACTHR / ACTH Receptor Rabbit anti-Human Polyclonal (aa86-135) (FITC) Antibody
Rat, Chimpanzee, Gibbon, Human
WB
FITC Conjugated
100 µl/$469
MC2R / ACTHR / ACTH Receptor Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
MC2R / ACTHR / ACTH Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
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product results
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