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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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MARK1 / MARK

MAP/microtubule affinity-regulating kinase 1

Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates DCX, MAP2, MAP4 and MAPT/TAU. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).

Gene Name: MAP/microtubule affinity-regulating kinase 1
Family/Subfamily: Protein Kinase , MARK
Synonyms: MARK1, KIAA1477, Par1c, PAR1 homolog c, MARK, Par-1c
Target Sequences: NM_018650 NP_061120.3 Q9P0L2

Publications (1)

1
Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. Hezel AF, Gurumurthy S, Granot Z, Swisa A, Chu GC, Bailey G, Dor Y, Bardeesy N, Depinho RA. Molecular and cellular biology. 2008 28:2414-25. [PubMed:18227155] [PMC:PMC2268441] Related Antibodies: LS-C98353.

Filtered by: None
Target
MARK1 / MARK (65)
Reactivity
Human (64)
Mouse (31)
Rat (4)
Bat (14)
Bovine (7)
Dog (7)
Hamster (1)
Horse (7)
Monkey (21)
Rabbit (21)
Application
IHC (45)
IHC-P (25)
WB (42)
Flo (7)
ELISA (36)
Peptide-ELISA (1)
Host
rabbit (64)
goat (1)
Isotype
IgG (38)
Clonality
polyclonal pc (65)
Format
AP Conjugated (7)
APC Conjugated (7)
Azide-free (7)
Biotin Conjugated (7)
FITC Conjugated (7)
HRP Conjugated (7)
PE Conjugated (7)
Unconjugated (23)
Epitope
N-Terminus (14)
aa6-40 (8)
aa600-627 (8)
aa643-674 (8)
aa671-700 (8)
Internal (7)
aa448-460 (1)
Publications
No (64)
Yes (1)
Showing 1-25 of 65 results

IHC-plus™ MARK1 / MARK Antibody (N-Terminus) LS-A9497
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Dog, Bovine, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50µg 0.75mg/ml  $425.00
Anti-MARK1 antibody IHC of human brain, caduate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ MARK1 / MARK Antibody (N-Terminus, Biotin) LS-A109447
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Dog, Bovine, Bat, Human, Monkey
IHC, IHC-P
Biotin Conjugated
100µl  $650.00
Anti-MARK1 antibody IHC of human brain, caduate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ MARK1 / MARK Antibody (N-Terminus, FITC) LS-A109448
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Dog, Bovine, Bat, Human, Monkey
IHC, IHC-P
FITC Conjugated
100µl  $650.00
Anti-MARK1 antibody IHC of human brain, caduate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ MARK1 / MARK Antibody (N-Terminus, APC) LS-A109446
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Dog, Bovine, Bat, Human, Monkey
IHC, IHC-P
APC Conjugated
100µl  $650.00
Anti-MARK1 antibody IHC of human brain, caduate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ MARK1 / MARK Antibody (N-Terminus, Azide-free, HRP) LS-A109449
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Dog, Bovine, Bat, Human, Monkey
IHC, IHC-P
HRP Conjugated, Azide-free
100µl  $650.00
Anti-MARK1 antibody IHC of human brain, caduate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ MARK1 / MARK Antibody (N-Terminus, PE) LS-A109450
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Dog, Bovine, Bat, Human, Monkey
IHC, IHC-P
PE Conjugated
100µl  $650.00
Anti-MARK1 antibody IHC of human brain, caduate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

MARK1 / MARK Antibody (aa6-40) LS-C98353
Publications (1)
Publications (1)
Rabbit Polyclonal to Human MARK1 / MARK
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400µl  $325.00
Formalin-fixed and paraffin-embedded human brain tissue reacted with MARK1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
The anti-MARK1 N-term antibody is used in Western blot to detect MARK1 in P7 mouse whole brain lysate (60 ug). 1:250 dilution of anti-MARK1 antibody was used. Data and protocol kindly provided by DR. Shengli Zhao, M.D., Ph.D. of Duke University Medical Center.

MARK1 / MARK Antibody (aa671-700) LS-C98354
Rabbit Polyclonal to Human MARK1 / MARK
Mouse, Human
WB
Unconjugated
400µl  $325.00
The anti-MARK1 C-term antibody is used in Western blot to detect MARK1 in, from left to right, HeLa, T47D, and mouse brain cell line/ tissue lysate.

MARK1 / MARK Antibody (aa643-674) LS-C322859
Rabbit Polyclonal (IgG) to Human MARK1 / MARK
Human
ELISA, Flo, IHC, WB
Unconjugated
200µl  $590.00

MARK1 / MARK Antibody (aa643-674, Biotin) LS-C262667
Rabbit Polyclonal (IgG) to Human MARK1 / MARK
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200µl  $740.00

MARK1 / MARK Antibody (aa643-674, FITC) LS-C262668
Rabbit Polyclonal (IgG) to Human MARK1 / MARK
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200µl  $740.00

MARK1 / MARK Antibody (aa643-674, AP) LS-C262665
Rabbit Polyclonal (IgG) to Human MARK1 / MARK
Human
ELISA, Flo, IHC, WB
AP Conjugated
200µl  $740.00

MARK1 / MARK Antibody (aa643-674, APC) LS-C262666
Rabbit Polyclonal (IgG) to Human MARK1 / MARK
Human
ELISA, Flo, IHC, WB
APC Conjugated
200µl  $740.00

MARK1 / MARK Antibody (aa643-674, Azide-free, HRP) LS-C262669
Rabbit Polyclonal (IgG) to Human MARK1 / MARK
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200µl  $740.00

MARK1 / MARK Antibody (aa643-674, PE) LS-C262670
Rabbit Polyclonal (IgG) to Human MARK1 / MARK
Human
ELISA, Flo, IHC, WB
PE Conjugated
200µl  $740.00

MARK1 / MARK Antibody LS-C676023
Rabbit Polyclonal (IgG) to Human MARK1 / MARK
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µl  $235.00; 100µl  $285.00
Immunohistochemistry of paraffin-embedded human brain tissue at dilution 1:100
Immunohistochemistry of paraffin-embedded human placenta tissue at dilution 1:100

MARK1 / MARK Antibody LS-C401346
Rabbit Polyclonal (IgG) to Human MARK1 / MARK
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20µl 0.2mg/ml  $205.00; 60µl 0.2mg/ml  $235.00; 120µl 0.2mg/ml  $295.00; 200µl 0.2mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human cervical cancer using MARK1 Polyclonal Antibody at dilution of 1:30.
Immunohistochemistry of paraffin-embedded Human colon cancer using MARK1 Polyclonal Antibody at dilution of 1:30.

MARK1 / MARK Antibody LS-C403317
Rabbit Polyclonal (IgG) to Human MARK1 / MARK
Human
ELISA, IHC, WB
Unconjugated
20µl 0.6mg/ml  $205.00; 60µl 0.6mg/ml  $235.00; 120µl 0.6mg/ml  $295.00; 200µl 0.6mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human brain using MARK1 Polyclonal Antibody at dilution of 1:40.
Immunohistochemistry of paraffin-embedded Human tonsil using MARK1 Polyclonal Antibody at dilution of 1:40.

IHC-plus™ MARK1 / MARK Antibody (Internal) LS-A9500
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-MARK1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ MARK1 / MARK Antibody (N-Terminus) LS-A9499
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Horse, Human, Monkey
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-MARK1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ MARK1 / MARK Antibody (N-Terminus, Biotin) LS-A109453
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Horse, Human, Monkey
IHC, IHC-P
Biotin Conjugated
100µl  $650.00
Anti-MARK1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ MARK1 / MARK Antibody (N-Terminus, APC) LS-A109452
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Horse, Human, Monkey
IHC, IHC-P
APC Conjugated
100µl  $650.00
Anti-MARK1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ MARK1 / MARK Antibody (N-Terminus, AP) LS-A109451
Rabbit Polyclonal to Human MARK1 / MARK
Rabbit, Horse, Human, Monkey
IHC, IHC-P
AP Conjugated
100µl  $650.00
Anti-MARK1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

MARK1 / MARK Antibody (aa6-40) LS-C322861
Rabbit Polyclonal (IgG) to Human MARK1 / MARK
Mouse, Human
ELISA, IHC, WB
Unconjugated
200µl  $590.00

MARK1 / MARK Antibody LS-C751971
Rabbit Polyclonal (IgG) to Human MARK1 / MARK
Human
ELISA, IHC, WB
Unconjugated
100µg  $335.00
Showing 1-25 of 65 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).