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MARCO
macrophage receptor with collagenous structure
MARCO is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.
| Gene Name: | macrophage receptor with collagenous structure |
| Synonyms: | MARCO, Macrophage receptor MARCO, Macrophage receptors marco, SCARA2 |
| Target Sequences: | NM_006770 NP_006761.1 Q9UEW3 |
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