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MAPRE2 / EB2 shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants.
Gene Name: | microtubule-associated protein, RP/EB family, member 2 |
Synonyms: | MAPRE2, APC-binding protein EB2, APC-binding protein EB1, EB1, EB2, End-binding protein 2 |
Target Sequences: | NM_014268 NP_055083.1 Q15555 |
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