LSBio
LSBio
Products
Services
Research Areas
Resources
Contact Us
Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

LSBio
2401 Fourth Avenue Suite 900
Seattle WA 98121

Phone: 866-819-4732 (Toll Free North America)
206-374-1102 (International)

Fax: 866-206-6909 (Toll Free North America)
206-577-4565 (International)

How to Buy - Details about how to buy our products.

Orders@LSBio.com - To submit a new order.

Customer.Support@LSBio.com - To submit questions about existing orders, pricing, availability, bulk quotes, proforma invoice requests, or other billing issues.

Technical.Support@LSBio.com - To request technical information requests about an LSBio product or its application.

Sales@LSBio.com - To request information about fee-for-service contract IHC studies, IHC reports, distribution agreements, or general business development.

Worldwide Distributors List - To find your local distributor if you're not within the United States.
Products
Services
Research Areas
Resources
Contact Us

MAP3K2 / MEKK2

mitogen-activated protein kinase kinase kinase 2

MEKK2, a MAP3K type protein kinase, is a member of MAP kinase signaling pathways. The protein contains a C-terminal protein kinase domain and a non-catalytic N-terminal domain. MEKK2 has been shown to regulate both JNK and ERK cascades by phosphorylating and activating either MKK4/MAP2K4 or MEK1/MAP2K1, respectively. Additionally, MEKK2 has been shown to directly phosphorylate and activate Ikappa B kinases (IKKs) of the immune and inflammatory response NF-kappa B signaling pathway and to bind and activate protein kinase C-related kinase 2. MEKK2 (-/-) embryonic stem cell-derived mast cells demonstrate that this protein is required for cytokine production and receptor-mediated stimulation of JNK.

Gene Name: mitogen-activated protein kinase kinase kinase 2
Family/Subfamily: Protein Kinase , MAP3K
Synonyms: MAP3K2, MAP/ERK kinase kinase 2, MAPK/ERK kinase kinase 2, MAPKKK2, MEK kinase 2, MEKK 2, MEKK2, MEKK2B
Target Sequences: NM_006609 NP_006600.3 Q9Y2U5

Filtered by: None
Target
MAP3K2 / MEKK2 (24)
Reactivity
Human (24)
Mouse (20)
Rat (9)
Bovine (6)
Chicken (1)
Chimpanzee (3)
Dog (7)
Gibbon (3)
Guinea pig (1)
Horse (6)
Monkey (5)
Pig (1)
Rabbit (2)
Xenopus (4)
Application
IHC (11)
IHC-P (1)
WB (22)
ELISA (11)
ICC (1)
IF (2)
IP (2)
Host
rabbit (22)
mouse (2)
Isotype
IgG (18)
IgG1 (2)
Clonality
monoclonal mc (2)
polyclonal pc (22)
Clone
4B4 (2)
Format
AP Conjugated (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (15)
Epitope
aa14-43 (8)
aa146-195 (4)
aa1-50 (2)
Internal (1)
aa125-175 (1)
aa606-619 (1)
Publications
No (24)
Showing 1-24 of 24 results

MAP3K2 / MEKK2 Antibody (clone 4B4) LS-C169422
Mouse Monoclonal [clone 4B4] (IgG1) to Human MAP3K2 / MEKK2
Human
ELISA IF IHC WB
Unconjugated
100µl  $365.00
Immunofluorescence of 3T3-L1 cells using MAP3K2 mouse monoclonal antibody (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
Western blot using MAP3K2 monoclonal antibody against human MAP3K2 (AA: 148-359) recombinant protein. (Expected MW is 49.2 kDa)

MAP3K2 / MEKK2 Antibody (clone 4B4) LS-C758680
Mouse Monoclonal [clone 4B4] (IgG1) to Human MAP3K2 / MEKK2
Mouse, Human
ICC IF WB
Unconjugated
100µl  $405.00
MEKK2 Antibody in Immunofluorescence (IF)
MEKK2 Antibody in Western Blot (WB)

MAP3K2 / MEKK2 Antibody (aa14-43) LS-C322834
Rabbit Polyclonal (IgG) to Mouse MAP3K2 / MEKK2
Mouse, Human
ELISA IHC WB
Unconjugated
200µl  $590.00

MAP3K2 / MEKK2 Antibody (aa14-43, Biotin) LS-C223191
Rabbit Polyclonal (IgG) to Human MAP3K2 / MEKK2
Mouse, Human
ELISA IHC WB
Biotin Conjugated
200µl  $740.00

MAP3K2 / MEKK2 Antibody (aa14-43, FITC) LS-C223192
Rabbit Polyclonal (IgG) to Human MAP3K2 / MEKK2
Mouse, Human
ELISA IHC WB
FITC Conjugated
200µl  $740.00

MAP3K2 / MEKK2 Antibody (aa14-43, AP) LS-C223190
Rabbit Polyclonal (IgG) to Human MAP3K2 / MEKK2
Mouse, Human
ELISA IHC WB
AP Conjugated
200µl  $740.00

MAP3K2 / MEKK2 Antibody (aa14-43, APC) LS-C223189
Rabbit Polyclonal (IgG) to Human MAP3K2 / MEKK2
Mouse, Human
ELISA IHC WB
APC Conjugated
200µl  $740.00

MAP3K2 / MEKK2 Antibody (aa14-43, PE) LS-C223194
Rabbit Polyclonal (IgG) to Human MAP3K2 / MEKK2
Mouse, Human
ELISA IHC WB
PE Conjugated
200µl  $740.00

MAP3K2 / MEKK2 Antibody (aa14-43, Azide-free, HRP) LS-C223193
Rabbit Polyclonal (IgG) to Human MAP3K2 / MEKK2
Mouse, Human
ELISA IHC WB
HRP Conjugated, Azide-free
200µl  $740.00

MAP3K2 / MEKK2 Antibody (aa14-43) LS-C164453
Rabbit Polyclonal to Mouse MAP3K2 / MEKK2
Mouse, Human
IHC IHC-P WB
Unconjugated
400µl  $325.00
Mouse Map3k2 immunohistochemistry of formalin-fixed and paraffin-embedded mouse pancreas tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
Mouse Map3k2 Antibody western blot of mouse kidney tissue lysates (35 ug/lane). The Map3k2 antibody detected the Map3k2 protein (arrow).

MAP3K2 / MEKK2 Antibody LS-C402651
Rabbit Polyclonal (IgG) to Human MAP3K2 / MEKK2
Mouse, Human
ELISA IHC
Unconjugated
20µl 0.3mg/ml  $205.00; 60µl 0.3mg/ml  $235.00; 120µl 0.3mg/ml  $295.00; 200µl 0.3mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human thyroid cancer using MAP3K2 Polyclonal Antibody at dilution of 1:15.
Immunohistochemistry of paraffin-embedded Human thyroid cancer using MAP3K2 Polyclonal Antibody at dilution of 1:15.

MAP3K2 / MEKK2 Antibody LS-C405902
Rabbit Polyclonal (IgG) to Human MAP3K2 / MEKK2
Mouse, Human
ELISA IHC
Unconjugated
20µl 0.4mg/ml  $205.00; 60µl 0.4mg/ml  $235.00; 120µl 0.4mg/ml  $295.00; 200µl 0.4mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human gastric cancer using MAP3K2 Polyclonal Antibody at dilution of 1:20.
Immunohistochemistry of paraffin-embedded Human gastric cancer using MAP3K2 Polyclonal Antibody at dilution of 1:20.

MAP3K2 / MEKK2 Antibody LS-C666729
Rabbit Polyclonal (IgG) to Human MAP3K2 / MEKK2
Human
ELISA WB
Unconjugated
100µg  $335.00

MAP3K2 / MEKK2 Antibody (aa125-175) LS-C288918
Rabbit Polyclonal (IgG) to Human MAP3K2 / MEKK2
Dog, Human
IP WB
Unconjugated
100µl 0.2mg/ml  $395.00

MAP3K2 / MEKK2 Antibody (aa1-50) LS-C288919
Rabbit Polyclonal (IgG) to Human MAP3K2 / MEKK2
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Human
IP WB
Unconjugated
100µl 0.2mg/ml  $395.00

MAP3K2 / MEKK2 Antibody LS-C340922
Rabbit Polyclonal to Human MAP3K2 / MEKK2
Mouse, Rat, Human
WB
Unconjugated
100µl 1mg/ml  $385.00

MAP3K2 / MEKK2 Antibody (aa1-50) LS-C47356
Rabbit Polyclonal (IgG) to Human MAP3K2 / MEKK2
Chicken, Bovine, Mouse, Dog, Rat, Horse, Human
WB
Unconjugated
100µg  $335.00
Western blot of human MEKK2in human liver cell lysate in the 1) absence and 2) presence of immunizing peptide using antibody at2 ug/ml.

MAP3K2 / MEKK2 Antibody (aa146-195) LS-C81354
Rabbit Polyclonal (IgG) to Human MAP3K2 / MEKK2
Xenopus, Rat, Horse, Mouse, Dog, Bovine, Human, Monkey
WB
Unconjugated
100µl 0.5mg/ml  $385.00
MCF7 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

MAP3K2 / MEKK2 Antibody (aa146-195, HRP) LS-C452169
Rabbit Polyclonal (IgG) to Human MAP3K2 / MEKK2
Xenopus, Rat, Mouse, Dog, Bovine, Horse, Human, Monkey, Chimpanzee, Gibbon
WB
HRP Conjugated
100µl 0.65mg/ml  $405.00
MCF7 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

MAP3K2 / MEKK2 Antibody (aa146-195, Biotin) LS-C452167
Rabbit Polyclonal (IgG) to Human MAP3K2 / MEKK2
Xenopus, Rat, Mouse, Dog, Bovine, Horse, Human, Monkey, Chimpanzee, Gibbon
WB
Biotin Conjugated
100µl 1mg/ml  $405.00
MCF7 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

MAP3K2 / MEKK2 Antibody (aa146-195, FITC) LS-C452168
Rabbit Polyclonal (IgG) to Human MAP3K2 / MEKK2
Xenopus, Rat, Mouse, Dog, Bovine, Horse, Human, Monkey, Chimpanzee, Gibbon
WB
FITC Conjugated
100µl 1mg/ml  $405.00
MCF7 cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

MAP3K2 / MEKK2 Antibody (aa606-619) LS-C312656
Rabbit Polyclonal to Human MAP3K2 / MEKK2
Rabbit, Rat, Pig, Human, Monkey
WB
Unconjugated
100µg 200µl 0.5mg/ml  $325.00
WB of MAP3K2 / MEKK2 antibody. All lanes: Anti-MAP3K2 at 0.5ug/ml. Lane 1: Rat Brain Tissue Lysate at 40ug. Lane 2: Rat Testis Tissue Lysate at 40ug. Lane 3: Rat Lung Tissue Lysate at 40ug. Predicted bind size: 70KD. Observed bind size: 70KD.

MAP3K2 / MEKK2 Antibody (Internal) LS-C353812
Rabbit Polyclonal to Human MAP3K2 / MEKK2
Mouse, Rat, Human
WB
Unconjugated
100µl 1mg/ml  $245.00
Western blot analysis of MEKK2 expression in A549 (A); Raw264.7 (B); H9C2 (C) whole cell lysates.

MAP3K2 / MEKK2 Antibody LS-C750112
Rabbit Polyclonal (IgG) to Human MAP3K2 / MEKK2
Mouse, Human
WB
Unconjugated
50µl  $235.00; 100µl  $295.00; 200µl  $385.00
Western blot analysis of extracts of mouse liver, using MAP3K2 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
Showing 1-24 of 24 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

Get Social With Us!
Follow us on Facebook Follow us on Google+ Follow us on LinkedIn PSL Alliance Member
Copyright © 2019 LifeSpan BioSciences, Inc. All Rights Reserved Privacy Policy