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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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Cell Cycle Pathways
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MAP2K2 / MKK2 / MEK2

mitogen-activated protein kinase kinase 2

MAP2K2 / MKK2 / MEK2 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene.

Gene Name: mitogen-activated protein kinase kinase 2
Family/Subfamily: Protein Kinase , MAP2K
Synonyms: MAP2K2, ERK activator kinase 2, MAP kinase kinase 2, MAPK/ERK kinase 2, MAPKK 2, MKK2, MEK 2, MEK2, MAPKK2, PRKMK2
Target Sequences: NM_030662 NP_109587.1 P36507

Viewing 1-25 of 155 items
MAP2K2 / MKK2 / MEK2 Antibody - Anti-MAP2K2 / MEK2 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal (IgG) to Human MAP2K2 / MKK2 / MEK2
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100µl   $485.00
MAP2K2 / MKK2 / MEK2 Antibody - Immunohistochemistry of paraffin-embedded mouse kidney using MAP2K1/MAP2K2 antibodyat dilution of 1:100 (40x lens).
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Rabbit Monoclonal to Human MAP2K2 / MKK2 / MEK2
Mouse, Rat, Human
IF, IHC, IP, WB
Unconjugated
50µl   $295.00; 100µl   $385.00; 200µl   $560.00
MAP2K2 / MKK2 / MEK2 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-MAP2K2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
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Mouse Monoclonal [clone OTI1A2] (IgG2a) to Human MAP2K2 / MKK2 / MEK2
Mouse, Dog, Rat, Human, Monkey
IF, IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $345.00
MAP2K2 / MKK2 / MEK2 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-MAP2K2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 120°C for 3min).
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Mouse Monoclonal [clone OTI1A2] (IgG2a) to Human MAP2K2 / MKK2 / MEK2
Mouse, Dog, Rat, Human, Monkey
IF, IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
MAP2K2 / MKK2 / MEK2 Antibody - MEK2 Antibody in Immunofluorescence (IF)
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Mouse Monoclonal [clone 7F5] (IgG1) to Human MAP2K2 / MKK2 / MEK2
Mouse, Rat, Human
Flo, ICC, IF, WB
Unconjugated
100µl   $425.00
MAP2K2 / MKK2 / MEK2 Antibody - IHC of paraffin-embedded Adenocarcinoma of breast tissue using anti-MAP2K2 mouse monoclonal antibody. (Dilution 1:50).
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Mouse Monoclonal [clone OTI5F6] (IgG1) to Human MAP2K2 / MKK2 / MEK2
Human
Flo, IHC, IHC-P, WB
Unconjugated
100µl   0.95mg/ml   $345.00
MAP2K2 / MKK2 / MEK2 Antibody - IHC of paraffin-embedded Adenocarcinoma of breast tissue using anti-MAP2K2 mouse monoclonal antibody. (Dilution 1:50).
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Mouse Monoclonal [clone OTI5F6] (IgG1) to Human MAP2K2 / MKK2 / MEK2
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
MAP2K2 / MKK2 / MEK2 Antibody - IHC of paraffin-embedded Carcinoma of pancreas tissue using anti-MAP2K2 mouse monoclonal antibody. (Dilution 1:50).
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Mouse Monoclonal [clone OTI8G6] (IgG1) to Human MAP2K2 / MKK2 / MEK2
Human
Flo, IHC, IHC-P, WB
Unconjugated
100µl   1mg/ml   $345.00
MAP2K2 / MKK2 / MEK2 Antibody - IHC of paraffin-embedded Carcinoma of pancreas tissue using anti-MAP2K2 mouse monoclonal antibody. (Dilution 1:50).
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Mouse Monoclonal [clone OTI8G6] (IgG1) to Human MAP2K2 / MKK2 / MEK2
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100µg   $395.00
MAP2K2 / MKK2 / MEK2 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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Rabbit Polyclonal to Human MAP2K2 / MKK2 / MEK2
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
400µl   $325.00
MAP2K2 / MKK2 / MEK2 Antibody - Immunohistochemistry of paraffin-embedded human liver cancer using MAP2K2 Antibody at dilution of 1:100
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Rabbit Polyclonal (IgG) to Human MAP2K2 / MKK2 / MEK2
Human
ELISA, IF, IHC, WB
Unconjugated
50µg   $285.00; 100µg   $385.00
MAP2K2 / MKK2 / MEK2 Antibody - Immunofluorescence (IF) analysis of HeLa cells using MEK-2 Monoclonal Antibody (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.
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Mouse Monoclonal (IgG1) to Human MAP2K2 / MKK2 / MEK2
Mouse, Rat, Human
ELISA, Flo, IF, WB
Unconjugated
100µl   $345.00
Select
Mouse Monoclonal (IgG1) to Human MAP2K2 / MKK2 / MEK2
Mouse, Rat, Human
ELISA, Flo, ICC, WB
Unconjugated
50µl   1mg/ml   $315.00; 100µl   1mg/ml   $375.00; 200µl   1mg/ml   $435.00
MAP2K2 / MKK2 / MEK2 Antibody - Immunofluorescence of HeLa cells using anti-MAP2K2 monoclonal antibody (green). Red: Actin filaments have been labeled with DY-554 phalloidin. Blue: DRAQ5 fluorescent DNA dye.
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Mouse Monoclonal [clone 7F5] (IgG1) to Human MAP2K2 / MKK2 / MEK2
Human
ELISA, Flo, IF, WB
Unconjugated
100µl   $345.00
MAP2K2 / MKK2 / MEK2 Antibody - Immunofluorescence staining of MAP2K2 in MCF7 cells. Cells were fixed with 4% PFA, permeabilzed with 0.1% Triton X-100 in PBS, blocked with 10% serum, and incubated with rabbit anti-Human MAP2K2 polyclonal antibody (dilution ratio 1:200) at 4°C overnight. Then cells were stained with the Alexa Fluor 488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to Cytoplasm.
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Rabbit Polyclonal (IgG) to Human MAP2K2 / MKK2 / MEK2
Human
ICC, IF, IP, WB
Unconjugated
50µl   $235.00; 100µl   $275.00; 200µl   $305.00
MAP2K2 / MKK2 / MEK2 Antibody
Select
Rabbit Polyclonal (IgG) to Human MAP2K2 / MKK2 / MEK2
Mouse, Rat, Human
ELISA, IF, IHC, IP, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
MAP2K2 / MKK2 / MEK2 Antibody
Select
Rabbit Polyclonal (IgG) to Human MAP2K2 / MKK2 / MEK2
Mouse, Rat, Human
ELISA, IHC, IP, WB
Unconjugated
100µl   1mg/ml   $325.00; 200µl   1mg/ml   $375.00
MAP2K2 / MKK2 / MEK2 Antibody - Immunofluorescence of monoclonal antibody to MAP2K2 on HeLa cell . [antibody concentration 10 ug/ml]
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Mouse Monoclonal [clone 8D10] (IgG2b,k) to Human MAP2K2 / MKK2 / MEK2
Human
ELISA, IF, WB
Unconjugated
100µg   $365.00
MAP2K2 / MKK2 / MEK2 Antibody - Western blot of MEK-2 antibody
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Rabbit Polyclonal (IgG) to Human MAP2K2 / MKK2 / MEK2
Mouse, Rat, Human
ELISA, IHC, IP, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
MAP2K2 / MKK2 / MEK2 Antibody - Western Blot (WB) analysis of VEC cells using Phospho-MEK-2 (T394) polyclonal antibody.
Select
Rabbit Polyclonal (IgG) to Human MAP2K2 / MKK2 / MEK2
Mouse, Rat, Human
ELISA, IHC, IP, WB
Unconjugated
50µl   1mg/ml   $235.00; 100µl   1mg/ml   $265.00; 200µl   1mg/ml   $335.00
MAP2K2 / MKK2 / MEK2 Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer using MAP2K2 Polyclonal Antibody at dilution of 1:100.
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Rabbit Polyclonal (IgG) to Human MAP2K2 / MKK2 / MEK2
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20µl   1mg/ml   $205.00; 60µl   1mg/ml   $235.00; 120µl   1mg/ml   $295.00; 200µl   1mg/ml   $395.00
MAP2K2 / MKK2 / MEK2 Antibody - Western blot analysis of extracts of HeLa cells, using MAP2K2 antibody. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking.
Select
Rabbit Polyclonal (IgG) to Human MAP2K2 / MKK2 / MEK2
Mouse, Human
IF, IHC, WB
Unconjugated
100µl   $295.00; 200µl   $385.00
MAP2K2 / MKK2 / MEK2 Antibody - IHC of MEK2 (R388) pAb in paraffin-embedded human breast carcinoma tissue.
Select
Rabbit Polyclonal to Human MAP2K2 / MKK2 / MEK2
Mouse, Rat, Human
IHC, IHC-P, IP, WB
Unconjugated
100µl   $345.00
MAP2K2 / MKK2 / MEK2 Antibody - Immunohistochemistry analysis of paraffin-embedded human breast carcinoma, using MEK2 Antibody. The picture on the right is blocked with the synthesized peptide.
Select
Rabbit Polyclonal (IgG) to Human MAP2K2 / MKK2 / MEK2
Mouse, Rat, Human
IHC, IHC-P, IP, Peptide-ELISA, WB
Unconjugated
50µl   1mg/ml   $265.00; 100µl   1mg/ml   $325.00
MAP2K2 / MKK2 / MEK2 Antibody - Immunohistochemical analysis of MKK2 (pT394) staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
Rabbit Polyclonal to Human MAP2K2 / MKK2 / MEK2
Human, Monkey
IHC, IHC-P, IP, WB
Unconjugated
100µl   1mg/ml   $265.00

Viewing 1-25 of 155 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).