MAFB

v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B

Acts as a transcriptional activator or repressor. Plays a pivotal role in regulating lineage-specific hematopoiesis by repressing ETS1-mediated transcription of erythroid-specific genes in myeloid cells. Required for monocytic, macrophage, podocyte and islet beta cell differentiation. Involved in renal tubule survival and F4/80 maturation. Activates the insulin and glucagon promoters. Together with PAX6, transactivates weakly the glucagon gene promoter through the G1 element. SUMO modification controls its transcriptional activity and ability to specify macrophage fate. Binds element G1 on the glucagon promoter (By similarity). Involved either as an oncogene or as a tumor suppressor, depending on the cell context.

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Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

MAFB (4)

Publications

No (4)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human MAFB Protein (Recombinant GST) (Full Length) - LS-G31857

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

62.2 kDa

Price:

10 µg/$479; 25 µg/$670

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Human MAFB Protein (Recombinant GST, N-terminus) (aa1-53) - LS-G61288

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human MAFB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82745

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.6 kDa

Price:

20 µg/$150

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MAFB Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100562

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.6 kDa

Price:

100 µg/$494

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