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B001/B101
Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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MAC-2-BP / LGALS3BP
lectin, galactoside-binding, soluble, 3 binding protein
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.
| Gene Name: | lectin, galactoside-binding, soluble, 3 binding protein |
| Synonyms: | LGALS3BP, 90K, Galectin-3-binding protein, Mac-2 BP, Mac-2-binding protein, MAC2BP, L3 antigen, Serum protein 90K, TANGO10B, BTBD17B, M2BP, MAC-2-BP, Tumor-associated antigen 90K |
| Target Sequences: | NM_005567 NP_005558.1 Q08380 |
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