LY96 / MD2 / MD-2

lymphocyte antigen 96

MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2; e. g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.

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Products

Proteins (12)

Type

Over-Expression Lysate (2)

Recombinant (10)

Target

LY96 / MD2 / MD-2 (12)

Application

SDS-PAGE (1)

Publications

No (12)

Tag

10His-GST, N-terminus + Myc, C-terminus (1)

6His-SUMO, N-terminus (1)

Fc, C-terminus (1)

GST (1)

His (1)

His, C-Terminal (1)

His, N-Terminal (1)

Human IgG Fc, C-terminus (1)

Myc-DDK (Flag) (4)

Species

Human (7)

Mouse (4)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (6)

Wheat Germ Extract (1)

Purification

Purified (3)

Low Endotoxin Level

Low endotoxin level (3)

Biologically Active

Biologically active (1)

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Mouse LY96 / MD2 / MD-2 Protein (Recombinant His, N-Terminal) (aa16-160) - LS-G15911

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

18.2 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Human LY96 / MD2 / MD-2 Protein (Recombinant His, C-Terminal) - LS-G136244

Source:

HEK 293 Cells

Tag:

His, C-Terminal

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

17.2 kDa

Price:

10 µg/$268; 50 µg/$349

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Human LY96 / MD2 / MD-2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G90116

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.4 kDa

Price:

20 µg/$150

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Human LY96 / MD2 / MD-2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71572

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.4 kDa

Price:

20 µg/$1,107

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LY96 / MD2 / MD-2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G113263

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18.4 kDa

Price:

100 µg/$494

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Human LY96 / MD2 / MD-2 Protein (Recombinant GST) (Full Length) - LS-G32936

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

41.36 kDa

Price:

10 µg/$479; 25 µg/$670

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Human LY96 / MD2 / MD-2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71573

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

15.4 kDa

Price:

20 µg/$1,107

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Human LY96 / MD2 / MD-2 Protein (Recombinant 10His-GST, N-terminus + Myc, C-terminus) (aa17-160) - LS-G56385

Source:

E. coli

Tag:

10His-GST, N-terminus + Myc, C-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Mouse LY96 / MD2 / MD-2 Protein (Recombinant 6His-SUMO, N-terminus) (aa19-160) - LS-G56391

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Mouse LY96 / MD2 / MD-2 Protein (Recombinant Human IgG Fc, C-terminus) (Met1-Asn160) - LS-G48941

Source:

HEK 293 Cells

Tag:

Human IgG Fc, C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant mouse LY96/Fc is a disulfide-linked homodimer. The reduced monomer comprises 383 amino acids and has a predicted molecular mass of 43.4 kDa. The apparent molecular mass of the protein is approximately 47 kDa in SDS-PAGE under reducing conditions.

Price:

100 µg/$441

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Mouse LY96 / MD2 / MD-2 Protein (Recombinant Fc, C-terminus) (Met1-Asn160) - LS-G138125

Source:

HEK 293 Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

43.4 kDa

Price:

100 µg/$721

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Human LY96 / MD2 / MD-2 Protein (Recombinant His) (aa19-160) - LS-G15915

Source:

E. coli

Tag:

His

Molecular Weight:

18.0 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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