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LRRC2 encodes a member of the leucine-rich repeat-containing family of proteins, which function in diverse biological pathways. This family member may possibly be a nuclear protein. Similarity to the RAS suppressor protein, as well as expression down-regulation observed in tumor cells, suggests that it may function as a tumor suppressor. The gene is located in the chromosome 3 common eliminated region 1 (C3CER1), a 1.4 Mb region that is commonly deleted in diverse tumors. A related pseudogene has been identified on chromosome 2.
Gene Name: | leucine rich repeat containing 2 |
Synonyms: | LRRC2 |
Target Sequences: | NM_024512 NP_078788.2 Q9BYS8 |
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