Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

LOXL2

lysyl oxidase-like 2

Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine). When secreted in extracellular matrix, promotes cross-linking of extracellular matrix proteins by mediating oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Acts as a regulator of sprouting angiogenesis, probably via collagen IV scaffolding. When nuclear, acts as a transcription corepressor and specifically mediates deamination of trimethylated 'Lys-4' of histone H3 (H3K4me3), a specific tag for epigenetic transcriptional activation. Involved in epithelial to mesenchymal transition (EMT) via interaction with SNAI1 and participates in repression of E-cadherin, probably by mediating deamination of histone H3. Also involved in E-cadherin repression following hypoxia, a hallmark of epithelial to mesenchymal transition believed to amplify tumor aggressiveness, suggesting that it may play a role in tumor progression. Acts as a regulator of chondrocyte differentiation, probably by regulating expression of factors that control chondrocyte differentiation.

Gene Name: lysyl oxidase-like 2
Synonyms: LOXL2, Lysyl oxidase-like protein 2, Lysyl oxidase related 2, Lysyl oxidase-like 2, WS9-14, LOR2, Lysyl oxidase homolog 2
Target Sequences: NM_002318 NP_002309.1 Q9Y4K0

Publications (1)

1
B lymphocytes directly contribute to tissue fibrosis in patients with IgG4-related disease. Emanuel Della-Torre, Elena Rigamonti, Cory Perugino, Simona Baghai-Sain, Na Sun, Naoki Kaneko, Takashi Maehara, Lucrezia Rovati, Maurilio Ponzoni, Raffaella Milani, Marco Lanzillotta, Vinay Mahajan, Hamid Mattoo, Ivan Molineris, Vikram Deshpande, John H Stone, Massimo Falconi, Angelo A Manfredi, Shiv Pillai. The Journal of allergy and clinical immunology. 2019 Mar;145:968-981e14. [Full Text Article] [PubMed:31319101] [PMC:PMC6960365] Related Antibodies: LS-A9350.

☰ Filters
Antibodies (87)
ELISA Kits (11)
Proteins (11)
Competitive EIA (1)
Custom (4)
Over-Expression Lysate (2)
Primary (87)
Recombinant (9)
Sandwich (6)
LOXL2 (109)
Human (61)
Mouse (28)
Rat (27)
Bat (4)
Bovine (5)
Chicken (4)
Dog (5)
Guinea pig (4)
Horse (5)
Monkey (5)
Orangutan (3)
Rabbit (5)
IHC (9)
IHC-P (7)
WB (74)
ELISA (18)
IF (1)
Peptide-ELISA (1)
SDS-PAGE (1)
rabbit (76)
mouse (11)
Product Group
IHCPlus (4)
IgG (19)
IgG1 (5)
IgG2a (2)
IgG2b (2)
IgG2b,k (1)
monoclonal mc (11)
polyclonal pc (76)
04 (1)
15 (1)
5D2 (1)
OTI2A7 (2)
OTI4H3 (2)
OTI8B2 (2)
OTI8G5 (2)
96-Well Microplate (1)
96-Well Strip Plate (10)
APC (5)
APC Conjugated (6)
Azide-free (1)
Biotin Conjugated (11)
Carrier-free (4)
Cy3 Conjugated (5)
Cy7 Conjugated (5)
FITC Conjugated (11)
HRP Conjugated (10)
PE Conjugated (6)
Preservative Free (3)
Unconjugated (33)
aa53-160 (11)
aa152-450 (8)
aa323-427 (8)
aa434-546 (8)
aa544-751 (8)
aa553-761 (8)
aa589-617 (7)
C-Terminus (4)
aa26-776 (4)
aa607-656 (4)
Internal (2)
N-Terminus (1)
aa454-742 (1)
aa739-770 (1)
No (108)
Yes (1)
Cell Culture Supernatants (3)
Cell Lysates (3)
Plasma (6)
Serum (6)
Tissue Homogenates (4)
GST, N-terminus (1)
His (6)
His, N-Terminal (1)
His,C-terminus (1)
Myc-DDK (Flag) (2)
Human (4)
Mouse (4)
Rat (2)
293T Cells (1)
E. coli (6)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Yeast (1)
Low endotoxin level (1)
Biologically active (1)
LOXL2 Antibody - Anti-LOXL2 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
LOXL2 Rabbit anti-Human Polyclonal (Internal) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Horse, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
LOXL2 Antibody - Anti-LOXL2 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
LOXL2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Rabbit, Dog, Bovine, Horse, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
LOXL2 Antibody - Anti-LOXL2 antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
Fast Shipping
LOXL2 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
LOXL2 Antibody - Anti-LOXL2 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Select
LOXL2 Rabbit anti-Human Polyclonal (aa454-742) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
LOXL2 Antibody - Western blot All lanes: Loxl2 antibody at 14µg/ml Lane 1: 293T whole cell lysate Lane 2: A549 whole cell lysate Lane 3: A431 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 88, 82 kDa Observed band size: 88 kDa
Select
LOXL2 Rabbit anti-Mouse Polyclonal (aa26-776) Antibody
Mouse, Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
LOXL2 Rabbit anti-Mouse Polyclonal (aa26-776) (Biotin) Antibody
Mouse
ELISA, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
LOXL2 Rabbit anti-Mouse Polyclonal (aa26-776) (FITC) Antibody
Mouse
ELISA, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
LOXL2 Antibody - IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-LOXL2 mouse monoclonal antibody. (Heat-induced epitope retrieval by Tris-EDTA, pH8.0)(1:150).
Select
LOXL2 Mouse anti-Human Monoclonal (aa152-450) (OTI8B2) Antibody
Human
IHC, IHC-P
Unconjugated
100 µl/$434
LOXL2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
LOXL2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$834
LOXL2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$854
LOXL2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$893
LOXL2 Antibody - Detection limit for recombinant GST tagged LOXL2 is approximately 0.3 ng/ml as a capture antibody.
Select
LOXL2 Mouse anti-Human Monoclonal (5D2) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
LOXL2 Protein
Select
E. coli
His
13.3 kDa
10 µg/$283; 50 µg/$452; 100 µg/$725; 200 µg/$905; 1 mg/$2,020; 500 µg/$1,558; 5 mg/$3,165; 2 mg/$2,209
LOXL2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum
1 Plate/$795
LOXL2 Antibody - Immunohistochemistry of paraffin-embedded human placenta tissue at dilution of 1:100
Select
LOXL2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
LOXL2 Antibody - LOXL2 antibody Western blot of Mouse Heart lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
LOXL2 Rabbit anti-Mouse Polyclonal (aa607-656) Antibody
Mouse
WB
Unconjugated
100 µl/$424
LOXL2 Antibody - Western blot of recombinant LOXL2.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
LOXL2 Rabbit anti-Human Polyclonal (aa323-427) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
LOXL2 Antibody
Select
LOXL2 Rabbit anti-Rat Polyclonal (aa434-546) (FITC) Antibody
Rat
WB
FITC Conjugated
100 µl/$359; 200 µl/$423; 500 µl/$655; 1 ml/$816; 2 ml/$1,055; 5 ml/$1,863
LOXL2 Protein - Recombinant Lysyl Oxidase Like Protein 2 By SDS-PAGE
Select
E. coli
His, N-Terminal
12.8 kDa
10 µg/$291; 50 µg/$502; 200 µg/$1,002; 1 mg/$2,144; 5 mg/$3,501; 2 mg/$2,334
Select
HEK 293 Cells
His,C-terminus
SDS-PAGE
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant mouse Loxl2 consists 762 amino acids and predicts a molecular mass of 85.9 kDa.
100 µg/$480
Select
LOXL2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
LOXL2 Rabbit anti-Human Polyclonal (aa589-617) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
LOXL2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
LOXL2 Antibody - HEK293T cells were transfected with the pCMV6-ENTRY control. (Left lane) or pCMV6-ENTRY LOXL2. (Right lane) cDNA for 48 hrs and lysed
Select
LOXL2 Mouse anti-Human Monoclonal (aa152-450) (OTI4H3) Antibody
Human
WB
Unconjugated
100 µl/$434
Viewing 1-25 of 109 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).