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LONP1 / LON

lon peptidase 1, mitochondrial

ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand-specific manner. May regulate mitochondrial DNA replication and/or gene expression using site-specific, single-stranded DNA binding to target the degradation of regulatory proteins binding to adjacent sites in mitochondrial promoters. Endogenous substrates include mitochondrial steroidogenic acute regulatory (StAR) protein.

Gene Name: lon peptidase 1, mitochondrial
Family/Subfamily: Protease , Serine S16
Synonyms: LONP1, HLON ATP-dependent protease, HLON, LON, Lon peptidase 1, mitochondrial, Lon protease, LONP, Mitochondrial lon peptidase 1, Protease, serine, 15, PRSS15, Lon protease-like protein, LonHS, Serine protease 15, Protease Serine 15
Target Sequences: NM_004793 NP_004784.2 P36776

☰ Filters
Antibodies (28)
Proteins (5)
Over-Expression Lysate (2)
Primary (28)
Recombinant (3)
LONP1 / LON (33)
Human (28)
Mouse (7)
Rat (1)
Rabbit (5)
IHC (5)
IHC-P (2)
WB (24)
ELISA (18)
IF (4)
IP (2)
Peptide-ELISA (1)
rabbit (21)
mouse (7)
Product Group
IHCPlus (1)
IgG (19)
IgG2a (1)
IgG2a,k (6)
monoclonal mc (7)
polyclonal pc (21)
APC Conjugated (3)
Azide-free (1)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (3)
Unconjugated (10)
aa389-418 (7)
aa661-761 (1)
aa909-959 (1)
No (33)
10His, N-terminus + Myc, C-terminus (1)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Drosophila melanogaster (1)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (2)
LONP1 / LON Antibody - Anti-LONP1 / LON antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
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LONP1 / LON Rabbit anti-Human Polyclonal (aa389-418) Antibody
Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
Select
LONP1 / LON Mouse anti-Human Monoclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$371
Select
LONP1 / LON Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$331
LONP1 / LON Antibody - 1:100 staining mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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LONP1 / LON Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
LONP1 / LON Antibody - Immunohistochemistry of paraffin-embedded human thyroid tissue at dilution of 1:100
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LONP1 / LON Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
Select
LONP1 / LON Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
LONP1 / LON Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
LONP1 / LON Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
LONP1 / LON Protein - 12.5% SDS-PAGE of human LONP1 stained with Coomassie Blue
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Wheat Germ Extract
GST
132.9 kDa
2 µg/$439
Select
LONP1 / LON Mouse anti-Human Monoclonal (aa661-761) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
Select
LONP1 / LON Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
Select
LONP1 / LON Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
Select
LONP1 / LON Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
Select
LONP1 / LON Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
Select
LONP1 / LON Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
Select
LONP1 / LON Rabbit anti-Human Polyclonal (aa389-418) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
LONP1 / LON Rabbit anti-Human Polyclonal (aa389-418) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
LONP1 / LON Rabbit anti-Human Polyclonal (aa389-418) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
LONP1 / LON Rabbit anti-Human Polyclonal (aa389-418) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
LONP1 / LON Rabbit anti-Human Polyclonal (aa389-418) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
Select
LONP1 / LON Rabbit anti-Human Polyclonal (aa389-418) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
LONP1 / LON Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
100 µg/$749
Select
LONP1 / LON Rabbit anti-Human Polyclonal (APC) Antibody
Rabbit, Mouse, Human
WB
APC Conjugated
100 µl/$937
LONP1 / LON Antibody
Select
LONP1 / LON Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
LONP1 / LON Antibody - Detection of human LONP1/PRSS15 by western blot. Samples: Whole cell lysate (50 µg) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-LONP1/PRSS15 antibody used for WB at 0.1 µg/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.
Select
LONP1 / LON Rabbit anti-Human Polyclonal (aa909-959) Antibody
Human
WB
Unconjugated
10 µl/$295; 100 µl/$514
Viewing 1-25 of 33 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).