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LMNB1 / Lamin B1

lamin B1

In animal cells, there are A- and B-type lamins, which differ in their length and isoelectric point (pI). Human cells have three differentially regulated genes. B-type lamins are present in every cell. B type lamins, B1 and B2, are expressed from the LMNB1 and LMNB2 genes on 5q23 and 19q13, respectively. A-type lamins are expressed only following gastrulation. Lamin A and C are the most common A-type lamins and are splice variants of the LMNA gene found at 1q21.

Gene Name:	lamin B1
Synonyms:	LMNB1, ADLD, Lamin B1, Lamin-B1, LMN, LMNB, LMN2
Target Sequences:	NM_005573 NP_005564.1 P20700

Publications (2)

Effect of estradiol on high glucose-induced osteoblast injury. Li G, Jiang X, Liu L, Liu X, Liu H, Zhang Z. Molecular medicine reports. 2019 October;20:3019-3026. [Full Text Article] [PubMed:31432111] [PMC:PMC6755179] Related Antibodies: LS-B6062.

Multisystem proteinopathy due to a homozygous p.Arg159His VCP mutation: A tale of the unexpected. Willem De Ridder, Abdelkrim Azmi, Christoph S Clemen, Ludwig Eichinger, Andreas Hofmann, Rolf Schröder, Katherine Johnson, Ana Töpf, Volker Straub, Peter De Jonghe, Stuart Maudsley, Jan L De Bleecker, Jonathan Baets. Neurology. 2020 February;94:e785-e796. [Full Text Article] [PubMed:31848255] Related Antibodies: LS-B11184.

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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