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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Telephone Numbers
Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
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Additional Contact Details
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LILRA5
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
LILRA5 is a member of the leukocyte immunoglobulin-like receptor (LIR) family. LIR family members are known to have activating and inibitory functions in leukocytes. Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines, which suggests the roles of this protein in triggering innate immune responses. This gene is one of the leukocyte receptor genes that form a gene cluster on the chromosomal region 19q13.4. Four alternatively spliced transcript variants encoding distinct isoforms have been described.
| Gene Name: | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5 |
| Family/Subfamily: | Immunoglobulin , not assigned-Immunoglobulin |
| Synonyms: | LILRA5, CD85, CD85F, CD85f antigen, ILT-11, ILT11, LILRB7, Leukocyte Ig-like receptor 9, LIR-9, LIR9 |
| Target Sequences: | NM_021250 NP_067073.1 A6NI73 |
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