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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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LIG1 / DNA Ligase 1

ligase I, DNA, ATP-dependent

LIG1 / DNA Ligase 1 is a member of the ATP-dependent DNA ligase protein family. The encoded protein functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. Disruption of this gene may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.

Gene Name: ligase I, DNA, ATP-dependent
Synonyms: LIG1, DNA ligase I, DNA ligase 1, Ligase I, DNA, ATP-dependent
Target Sequences: NM_000234 NP_000225.1 P18858

Filtered by: None
Type
Over-Expression Lysate (4)
Recombinant (6)
Target
LIG1 / DNA Ligase 1 (10)
Tag
GST (1)
GST,N-terminus (3)
His (1)
His + T7 (1)
His, N-Terminal (1)
Myc + DDK (3)
Species
Human (6)
Rat (1)
Source
293T Cells (1)
E. coli (5)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Yeast (1)
Purification
Purified (2)
Publications
No (10)
Showing 1-10 of 10 results

Human LIG1 / DNA Ligase 1 Protein (Recombinant His, N-Terminal) (aa484-663) - LS-G13583
E. coli
His, N-Terminal
24.4 kDa
10µg  $295.00; 50µg  $485.00; 100µg  $680.00; 200µg  $980.00; 1mg  $2,535.00; 500µg  $1,125.00
Recombinant ATP Dependent DNA ligase I By SDS-PAGE

Human LIG1 / DNA Ligase 1 Protein (Recombinant His) (Full Length) - LS-G23008
Yeast
His
103.7 kD
1000µg  $1,500.00; 500µg  $950.00; 200µg  $560.00; 50µg  $295.00; 10µg  $255.00; 100µg  $385.00

LIG1 / DNA Ligase 1 Protein (Over-Expression Lysate GST,N-terminus) - LS-G42302
E. coli
GST,N-terminus
46 kDa
200µg  $315.00

LIG1 / DNA Ligase 1 Protein (Over-Expression Lysate GST,N-terminus) - LS-G42305
E. coli
GST,N-terminus
55 kDa
200µg  $315.00

Human LIG1 / DNA Ligase 1 Protein (Recombinant GST) (Full Length) - LS-G20927
E. coli
GST
129.1 kD
1000µg  $1,245.00; 500µg  $785.00; 200µg  $475.00; 50µg  $275.00; 10µg  $235.00; 100µg  $355.00

Human LIG1 / DNA Ligase 1 Protein (Recombinant GST,N-terminus) (aa810-919) - LS-G59118
Wheat Germ Extract
GST,N-terminus
10µg  $425.00; 25µg  $590.00
12.5% SDS-PAGE Stained with Coomassie Blue.

Rat LIG1 / DNA Ligase 1 Protein (Recombinant His + T7) (aa568-875) - LS-G13584
E. coli
His + T7
39.0 kDa
50µg  $515.00; 10µg  $295.00; 200µg  $1,020.00; 100µg  $710.00; 1mg  $2,640.00; 500µg  $1,170.00
Recombinant ATP Dependent DNA ligase I By SDS-PAGE

LIG1 / DNA Ligase 1 Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G123315
HEK 293 Cells
Myc + DDK
101.6 kDa
100µg  $365.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

Human LIG1 / DNA Ligase 1 Protein (Over-Expression Lysate Myc + DDK) (Full Length) - LS-G75542
293T Cells
Myc + DDK
101.6 kDa
20µg  $195.00
Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate

Human LIG1 / DNA Ligase 1 Protein (Recombinant Myc + DDK) (Full Length) - LS-G65432
HEK 293 Cells
Myc + DDK
101.6 kDa
20µg  $950.00
Purified recombinant protein LIG1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Showing 1-10 of 10 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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