LGMN / Legumain

legumain

LGMN / Legumain is a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform.

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Products

Proteins (19)

Type

Over-Expression Lysate (4)

Recombinant (15)

Target

LGMN / Legumain (19)

Publications

No (19)

Tag

10His, N-terminus + Myc, C-terminus (2)

6His, C-terminus (4)

6His, N-terminus (5)

GST (1)

His (1)

His, N-Terminal (1)

Myc-DDK (Flag) (5)

Species

Crab-eating macaque (2)

Human (9)

Mouse (6)

Source

293T Cells (2)

Baculovirus (1)

E. coli (5)

HEK 293 Cells (3)

Human Cells (3)

Mammalian Cells (2)

Wheat Germ Extract (1)

Yeast (2)

Purification

Purified (10)

Low Endotoxin Level

Low endotoxin level (5)

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Human LGMN / Legumain Protein (Recombinant 6His, N-terminus) (aa18-433) - LS-G24951

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

51.4 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Human LGMN / Legumain Protein (Recombinant 6His, N-terminus) (aa18-323) - LS-G56376

Source:

E. coli

Tag:

6His, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Mouse LGMN / Legumain Protein (Recombinant 6His, N-terminus) (aa18-325) - LS-G56378

Source:

E. coli

Tag:

6His, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human LGMN / Legumain Protein (Recombinant 6His, C-terminus) (Ile18-Tyr433) - LS-G38896

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

48.72kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157

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Human LGMN / Legumain Protein (Recombinant 6His, N-terminus) (aa18-323) - LS-G57213

Source:

Yeast

Tag:

6His, N-terminus

Price:

100 µg/$499; 20 µg/$364; 1 mg/$1,683

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Mouse LGMN / Legumain Protein (Recombinant 6His, N-terminus) (aa18-325) - LS-G57215

Source:

Yeast

Tag:

6His, N-terminus

Price:

100 µg/$570; 20 µg/$395; 1 mg/$1,973

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LGMN / Legumain Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115847

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.67 kDa

Price:

100 µg/$494

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LGMN / Legumain Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99278

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.43 kDa

Price:

100 µg/$494

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Mouse LGMN / Legumain Protein (Recombinant His, N-Terminal) (Val18-Tyr435) - LS-G24952

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

51.3 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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Mouse LGMN / Legumain Protein (Recombinant 6His, C-terminus) (Val18-Tyr435) - LS-G40041

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

48.7kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,353

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Human LGMN / Legumain Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77081

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.43 kDa

Price:

20 µg/$150

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Human LGMN / Legumain Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77083

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.67 kDa

Price:

20 µg/$150

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Human LGMN / Legumain Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66167

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.6 kDa

Price:

20 µg/$1,107

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Mouse LGMN / Legumain Protein (Recombinant His) (Val18-Tyr435) - LS-G98809

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

49.8 kDa

Price:

50 µg/$854

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Crab-eating macaque LGMN / Legumain Protein (Recombinant 10His, N-terminus + Myc, C-terminus) (Full Length) - LS-G137053

Source:

E. coli

Tag:

10His, N-terminus + Myc, C-terminus

Molecular Weight:

39.7 kDa

Price:

1 mg/$1,679; 100 µg/$598; 20 µg/$405

Select

Human LGMN / Legumain Protein (Recombinant 6His, C-terminus) (Ile18-Tyr433) - LS-G140257

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

48.7 kDa

Price:

10 µg/$344; 50 µg/$584

Select

Mouse LGMN / Legumain Protein (Recombinant 6His, C-terminus) (Val18-Tyr435) - LS-G140674

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

48.7 kDa

Price:

10 µg/$344; 50 µg/$584

Select

Crab-eating macaque LGMN / Legumain Protein (Recombinant 10His, N-terminus + Myc, C-terminus) (Full Length) - LS-G136843

Source:

Baculovirus

Tag:

10His, N-terminus + Myc, C-terminus

Molecular Weight:

38.7 kDa

Price:

100 µg/$1,164; 20 µg/$475; 1 mg/$2,187

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Human LGMN / Legumain Protein (Recombinant GST) (Full Length) - LS-G29948

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

73.15 kDa

Price:

2 µg/$439

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