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LEFTYB / LEFTY1

left-right determination factor 1

LEFTYB / LEFTY1 is a member of the TGF-beta family of proteins. A similar secreted protein in mouse plays a role in left-right asymmetry determination of organ systems during development. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene.

Gene Name: left-right determination factor 1
Family/Subfamily: TGF beta , not assigned-TGF beta
Synonyms: LEFTY1, LEFTYB, Protein lefty-B, LEFTB, Protein lefty-1
Target Sequences: NM_020997 NP_066277.1 O75610

Publications (2)

1
Quantitative Profiling of Single Formalin Fixed Tumour Sections: proteomics for translational research. Hughes CS, McConechy MK, Cochrane DR, Nazeran T, Karnezis AN, Huntsman DG, Morin GB. Scientific reports. 2016 6:34949. (WB; Human) [Full Text Article] [PubMed:27713570] [PMC:PMC5054533] Related Antibodies: LS-B5830.
2
MicroRNAs regulate p21(Waf1/Cip1) protein expression and the DNA damage response in human embryonic stem cells. Dolezalova D, Mraz M, Barta T, Plevova K, Vinarsky V, Holubcova Z, Jaros J, Dvorak P, Pospisilova S, Hampl A. Stem cells (Dayton, Ohio). Jul;30:1362-72. [Full Text Article] [PubMed:22511267] Related Antibodies: LS-C100882.

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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).