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LEFTYB / LEFTY1

left-right determination factor 1

LEFTYB / LEFTY1 is a member of the TGF-beta family of proteins. A similar secreted protein in mouse plays a role in left-right asymmetry determination of organ systems during development. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene.

Gene Name: left-right determination factor 1
Family/Subfamily: TGF beta , not assigned-TGF beta
Synonyms: LEFTY1, LEFTYB, Protein lefty-B, LEFTB, Protein lefty-1
Target Sequences: NM_020997 NP_066277.1 O75610

Publications (2)

1
Quantitative Profiling of Single Formalin Fixed Tumour Sections: proteomics for translational research. Hughes CS, McConechy MK, Cochrane DR, Nazeran T, Karnezis AN, Huntsman DG, Morin GB. Scientific reports. 2016 6:34949. (WB; Human) [Full Text Article] [PubMed:27713570] [PMC:PMC5054533] Related Antibodies: LS-B5830.
2
MicroRNAs regulate p21(Waf1/Cip1) protein expression and the DNA damage response in human embryonic stem cells. Dolezalova D, Mraz M, Barta T, Plevova K, Vinarsky V, Holubcova Z, Jaros J, Dvorak P, Pospisilova S, Hampl A. Stem cells (Dayton, Ohio). Jul;30:1362-72. [Full Text Article] [PubMed:22511267] Related Antibodies: LS-C100882.

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Products
Antibodies (74)
Primary (74)
LEFTYB / LEFTY1 (74)
Human (58)
Mouse (26)
Rat (19)
Pig (8)
IHC (5)
IHC-P (5)
WB (63)
ELISA (11)
ICC (2)
Peptide-ELISA (1)
rabbit (60)
mouse (14)
Product Group
IHCPlus (1)
IgG (12)
IgG2a,k (6)
monoclonal mc (14)
polyclonal pc (60)
APC (6)
APC Conjugated (8)
Biotin Conjugated (11)
Cy3 Conjugated (6)
Cy7 Conjugated (6)
FITC Conjugated (11)
HRP Conjugated (10)
PE Conjugated (8)
Unconjugated (14)
aa169-368 (16)
aa43-364 (10)
aa167-332 (8)
aa78-361 (8)
N-Terminus (4)
aa283-314 (1)
No (72)
Yes (2)
LEFTYB / LEFTY1 Antibody - Anti-LEFTY1 / Lefty antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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LEFTYB / LEFTY1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
LEFTYB / LEFTY1 Antibody - Anti-LEFTY1 / Lefty antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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LEFTYB / LEFTY1 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Human
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
LEFTYB / LEFTY1 Antibody - Anti-LEFTY1 / Lefty antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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LEFTYB / LEFTY1 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Human
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
LEFTYB / LEFTY1 Antibody - Anti-LEFTY1 / Lefty antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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LEFTYB / LEFTY1 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Human
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
LEFTYB / LEFTY1 Antibody - Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with LEFTB antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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LEFTYB / LEFTY1 Rabbit anti-Human Polyclonal (aa283-314) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
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LEFTYB / LEFTY1 Mouse anti-Human Monoclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$705
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LEFTYB / LEFTY1 Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA, WB
HRP Conjugated
100 µl/$904
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LEFTYB / LEFTY1 Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µl/$904
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LEFTYB / LEFTY1 Mouse anti-Human Monoclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
100 µl/$904
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LEFTYB / LEFTY1 Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA, WB
PE Conjugated
100 µl/$904
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LEFTYB / LEFTY1 Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA, WB
APC Conjugated
100 µl/$904
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LEFTYB / LEFTY1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
LEFTYB / LEFTY1 Antibody - Positive WB detected in:Rat spleen tissue,Mouse heart tissue,Mouse liver tissue,Mouse brain tissue;All lanes:LEFTY1 antibody at 2.7?g/ml;Secondary;Goat polyclonal to rabbit IgG at 1/50000 dilution;Predicted band size: 41 KDa;Observed band size: 41 KDa;
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LEFTYB / LEFTY1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
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LEFTYB / LEFTY1 Rabbit anti-Human Polyclonal (aa43-364) (FITC) Antibody
Human
ICC, WB
FITC Conjugated
100 µl/$328
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LEFTYB / LEFTY1 Rabbit anti-Human Polyclonal (aa43-364) (Biotin) Antibody
Human
ICC, WB
Biotin Conjugated
100 µl/$318
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LEFTYB / LEFTY1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
LEFTYB / LEFTY1 Antibody - Western Blot; Sample: Recombinant LEFTY1, Mouse.
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LEFTYB / LEFTY1 Rabbit anti-Mouse Polyclonal (aa169-368) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
LEFTYB / LEFTY1 Antibody - Western Blot; Sample: Recombinant LEFTY1, Mouse.
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LEFTYB / LEFTY1 Rabbit anti-Mouse Polyclonal (aa169-368) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
LEFTYB / LEFTY1 Antibody - Western Blot; Sample: Recombinant LEFTY1, Mouse.
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LEFTYB / LEFTY1 Rabbit anti-Mouse Polyclonal (aa169-368) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765
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LEFTYB / LEFTY1 Mouse anti-Human Monoclonal Antibody
Human
Unconjugated
100 µl/$314; 200 µl/$359; 500 µl/$507; 1 ml/$581; 2 ml/$798; 5 ml/$1,296
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LEFTYB / LEFTY1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
100 µg/$749
LEFTYB / LEFTY1 Antibody - Western blot of recombinant LEFTYB / LEFTY1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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LEFTYB / LEFTY1 Rabbit anti-Human Polyclonal (aa167-332) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
LEFTYB / LEFTY1 Antibody - Western blot analysis of extracts of various cell lines, using LEFTY1 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 1s.
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LEFTYB / LEFTY1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
LEFTYB / LEFTY1 Antibody - Western blot of recombinant LEFTYB / LEFTY1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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LEFTYB / LEFTY1 Rabbit anti-Human Polyclonal (aa78-361) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
LEFTYB / LEFTY1 Antibody - Western blot of LEFTYB / LEFTY1 antibody.
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LEFTYB / LEFTY1 Rabbit anti-Human Polyclonal (aa43-364) Antibody
Pig, Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).