LDLR / LDL Receptor

low density lipoprotein receptor

The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.

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Products

Proteins (20)

Type

Over-Expression Lysate (6)

Recombinant (14)

Target

LDLR / LDL Receptor (20)

Application

Bind (2)

ELISA (2)

Func (2)

SDS-PAGE (2)

Publications

No (20)

Tag

6His, C-terminus (2)

6His-AVI, C-terminus (1)

GST (1)

GST, N-terminus (1)

His (2)

His,C-terminus (2)

His-GST (1)

His-T7 (2)

His-T7, N-terminus (1)

Myc-DDK (Flag) (7)

Species

Human (12)

Mouse (4)

Rat (1)

Source

293T Cells (3)

E. coli (4)

HEK 293 Cells (6)

Human Cells (3)

Mammalian Cells (2)

Wheat Germ Extract (2)

Purification

Purified (4)

Low Endotoxin Level

Low endotoxin level (7)

Biologically Active

Biologically active (2)

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Mouse LDLR / LDL Receptor Protein (Recombinant His,C-terminus) (Met1-Arg790) - LS-G49337

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

Bind ELISA Func SDS-PAGE

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The secreted recombinant mouse LDLR comprises 780 amino acids with a predicted molecular mass of 85.7 kDa. As a result of glycosylation, it migarates as approximately 120-130 kDa protein in SDS-PAGE under reducing conditions.

Price:

50 µg/$364; 500 µg/$1,452

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Human LDLR / LDL Receptor Protein (Recombinant His,C-terminus) (Met1-Arg788) - LS-G48798

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

Bind ELISA Func SDS-PAGE

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The secreted recombinant human LDLR comprises 777 amino acids with a predicted molecular mass of 86 kDa. As a result of different glycosylation, it migarates with the apparent molecular mass of 110-140 kDa in SDS-PAGE under reducing conditions corresponding to the mature and immature form.

Price:

50 µg/$364; 1 mg/$2,003

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LDLR / LDL Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99068

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

95.38 kDa

Price:

100 µg/$494

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Human LDLR / LDL Receptor Protein (Recombinant His) (Met1-Arg788) - LS-G98621

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

86 kDa

Price:

50 µg/$649

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LDLR / LDL Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G131090

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

76.3 kDa

Price:

100 µg/$710

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LDLR / LDL Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G131096

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

77.3 kDa

Price:

100 µg/$710

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Human LDLR / LDL Receptor Protein (Recombinant His-T7) (aa497-742) - LS-G13203

Source:

E. coli

Tag:

His-T7

Molecular Weight:

31.1 kDa

Price:

50 µg/$422; 10 µg/$278; 200 µg/$842; 100 µg/$672; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Mouse LDLR / LDL Receptor Protein (Recombinant His-GST) (aa263-509) - LS-G24181

Source:

E. coli

Tag:

His-GST

Molecular Weight:

60.1 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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Rat LDLR / LDL Receptor Protein (Recombinant His-T7) (aa335-588) - LS-G24182

Source:

E. coli

Tag:

His-T7

Molecular Weight:

32.3 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Human LDLR / LDL Receptor Protein (Recombinant 6His, C-terminus) (Ala22-Arg788) - LS-G39341

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

84.78kD

Price:

10 µg/$288; 50 µg/$435; 500 µg/$1,585; 1 mg/$2,157

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Human LDLR / LDL Receptor Protein (Recombinant GST, N-terminus) (aa105-205) - LS-G59108

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human LDLR / LDL Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77128

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

95.38 kDa

Price:

20 µg/$150

Select

Human LDLR / LDL Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77129

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

77.3 kDa

Price:

20 µg/$215

Select

Human LDLR / LDL Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77130

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

76.3 kDa

Price:

20 µg/$215

Select

Human LDLR / LDL Receptor Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66186

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

93 kDa

Price:

20 µg/$1,107

Select

Mouse LDLR / LDL Receptor Protein (Recombinant His) (Met1-Arg790) - LS-G98808

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

85.7 kDa

Price:

50 µg/$649

Select

Human LDLR / LDL Receptor Protein (Recombinant 6His, C-terminus) (Ala22-Arg788) - LS-G139921

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

84.8 kDa

Price:

10 µg/$288; 50 µg/$428

Select

Mouse LDLR / LDL Receptor Protein (Recombinant His-T7, N-terminus) (Asp25-Gly186) - LS-G133488

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

21.3kDa

Price:

10 µg/$271; 50 µg/$382; 200 µg/$762; 100 µg/$610; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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Human LDLR / LDL Receptor Protein (Recombinant 6His-AVI, C-terminus) (Ala22-Arg788) - LS-G140265

Source:

Mammalian Cells

Tag:

6His-AVI, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

90.1 kDa

Price:

20 µg/$466; 100 µg/$1,103

Select

Human LDLR / LDL Receptor Protein (Recombinant GST) (Full Length) - LS-G29186

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

120.23 kDa

Price:

2 µg/$439

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