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LBP

lipopolysaccharide binding protein

LBP is involved in the acute-phase immunologic response to gram-negative bacterial infections. Gram-negative bacteria contain a glycolipid, lipopolysaccharide (LPS), on their outer cell wall. Together with bactericidal permeability-increasing protein (BPI), the encoded protein binds LPS and interacts with the CD14 receptor, probably playing a role in regulating LPS-dependent monocyte responses. Studies in mice suggest that the encoded protein is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. This protein is part of a family of structurally and functionally related proteins, including BPI, plasma cholesteryl ester transfer protein (CETP), and phospholipid transfer protein (PLTP).

Gene Name: lipopolysaccharide binding protein
Synonyms: LBP, BPIFD2, LPS-binding protein
Target Sequences: NM_004139 NP_004130.2 P18428

Publications (2)

1
Use of aspirin to intentionally induce gastrointestinal tract barrier dysfunction in feedlot cattle. Nathan G Briggs, Kristen M Brennan, Bethany J Funnell, Griffin T Nicholls, Jon P Schoonmaker. Journal of animal science. 2020 Sep;98:skaa264. [Full Text Article] [PubMed:32815992] [PMC:PMC7497817]
2
Histamine promotes adhesion of neutrophils by inhibition of autophagy in dairy cows with subacute ruminal acidosis. Kexin Wang, Zhenai Sun, Yunfei Li, Mingchao Liu, Juan J Loor, Qianming Jiang, Guowen Liu, Zhe Wang, Yuxiang Song, Xinwei Li. Journal of dairy science. 2022 September;105:7600-7614. [Full Text Article] [PubMed:35940921]

☰ Filters
Products
Proteins (14)
Over-Expression Lysate (2)
Recombinant (12)
LBP (14)
No (14)
6His, C-terminus (2)
GST (1)
His (2)
His, N-Terminal (3)
His-GST (1)
His-T7 (3)
Myc-DDK (Flag) (2)
Bovine (1)
Human (6)
Mouse (2)
Pig (1)
Rabbit (1)
Rat (2)
293T Cells (1)
E. coli (9)
HEK 293 Cells (1)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (3)
LBP Protein - Recombinant Lipopolysaccharide Binding Protein By SDS-PAGE
Select
E. coli
His, N-Terminal
52.4 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
LBP Protein - Recombinant Lipopolysaccharide Binding Protein By SDS-PAGE
Select
E. coli
His, N-Terminal
27.6 kDa
10 µg/$279; 50 µg/$430; 100 µg/$687; 200 µg/$857; 1 mg/$1,956; 500 µg/$1,499; 5 mg/$2,997; 2 mg/$2,142
LBP Protein - Recombinant Lipopolysaccharide Binding Protein By SDS-PAGE
Select
E. coli
His, N-Terminal
31.3 kDa
10 µg/$286; 50 µg/$472; 200 µg/$942; 1 mg/$2,069; 5 mg/$3,291; 2 mg/$2,257
LBP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
53.38 kDa
100 µg/$710
LBP Protein - Recombinant Lipopolysaccharide Binding Protein By SDS-PAGE
Select
E. coli
His
56.5 kDa
10 µg/$289; 50 µg/$492; 100 µg/$785; 200 µg/$982; 1 mg/$2,119; 500 µg/$1,646; 5 mg/$3,431; 2 mg/$2,309
LBP Protein - Recombinant  Lipopolysaccharide Binding Protein By SDS-PAGE
Select
E. coli
His-GST
81.72 kDa
10 µg/$281; 50 µg/$440; 100 µg/$702; 200 µg/$877; 1 mg/$1,983; 500 µg/$1,523; 5 mg/$3,067; 2 mg/$2,170
LBP Protein - 12.5% SDS-PAGE of human LBP stained with Coomassie Blue
Select
Wheat Germ Extract
GST
75.46 kDa
10 µg/$479; 25 µg/$670
LBP Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
53.38 kDa
20 µg/$215
Select
E. coli
111 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
12.32 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
52.0 kDa
10 µg/$297; 50 µg/$460
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
51.95kD
10 µg/$297; 50 µg/$468; 500 µg/$1,585; 1 mg/$2,157
LBP Protein - Recombinant Lipopolysaccharide Binding Protein By SDS-PAGE
Select
E. coli
His-T7
54.5 kDa
10 µg/$279; 50 µg/$430; 100 µg/$687; 200 µg/$857; 1 mg/$1,956; 500 µg/$1,499; 5 mg/$2,997; 2 mg/$2,142
LBP Protein - Recombinant Lipopolysaccharide Binding Protein By SDS-PAGE
Select
E. coli
His-T7
32.6 kDa
10 µg/$281; 50 µg/$440; 100 µg/$702; 200 µg/$877; 1 mg/$1,983; 500 µg/$1,523; 5 mg/$3,067; 2 mg/$2,170
LBP Protein - Recombinant Lipopolysaccharide Binding Protein By SDS-PAGE
Select
E. coli
His-T7
32.1 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).