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Has (dihydro)ceramide synthesis activity with relatively broad substrate specificity, but a preference for C18:0 and other middle- to long-chain fatty acyl-CoAs By similarity. It is crucial for the synthesis of very long-chain ceramides in the epidermis, to maintain epidermal lipid homeostasis and terminal differentiation.
Gene Name: | ceramide synthase 3 |
Synonyms: | CERS3, Ceramide synthase 3, LASS3 |
Target Sequences: | NM_178842 NP_849164.2 Q8IU89 |
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