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Catalyzes the specific attachment of an amino acid to its cognate tRNA in a two step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Exhibits a post-transfer editing activity to hydrolyze mischarged tRNAs.
Gene Name: | leucyl-tRNA synthetase |
Synonyms: | LARS, Hr025Cl, HSPC192, LARS1, Leucyl-tRNA synthetase, LEURS, PIG44, KIAA1352, Leucine translase, LEUS, LRS, RNTLS, Leucine-tRNA ligase, Proliferation-inducing gene 44 |
Target Sequences: | NM_020117 NP_064502.9 Q9P2J5 |
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