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LAMTOR3 / MP1

late endosomal/lysosomal adaptor, MAPK and MTOR activator 3

As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances the efficiency of the MAP kinase cascade facilitating the activation of MAPK2.

Gene Name: late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
Synonyms: LAMTOR3, MAPBP, MAPK scaffold protein 1, MAPKSP1, MAP2K1IP1, MEK binding partner 1, MEK-binding partner 1, MP1, Ragulator3, PRO0633
Target Sequences: NM_021970 NP_068805.1 Q9UHA4

☰ Filters
Products
Proteins (9)
Over-Expression Lysate (2)
Recombinant (7)
LAMTOR3 / MP1 (9)
No (9)
6His, N-terminus (2)
GST (1)
GST, N-terminus (2)
His (1)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (8)
293T Cells (1)
E. coli (5)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (2)
Low endotoxin level (2)
LAMTOR3 / MP1 Protein
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E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
LAMTOR3 / MP1 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
GST, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
LAMTOR3 / MP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
13.4 kDa
100 µg/$494
LAMTOR3 / MP1 Protein - Recombinant Mitogen Activated Protein Kinase Scaffold Protein 1 By SDS-PAGE
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E. coli
His-T7
17.4 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
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E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
15.78kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
LAMTOR3 / MP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
13.4 kDa
20 µg/$150
LAMTOR3 / MP1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
15.8 kDa
10 µg/$344; 50 µg/$584
LAMTOR3 / MP1 Protein - 12.5% SDS-PAGE of human MAPKSP1 stained with Coomassie Blue
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Wheat Germ Extract
GST
40 kDa
10 µg/$479; 25 µg/$670
Viewing 1-9 of 9 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).