LAMC3 / Laminin Gamma 3

laminin, gamma 3

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Laminins are composed of 3 non identical chains: laminin alpha, beta and gamma (formerly A, B1, and B2, respectively) and they form a cruciform structure consisting of 3 short arms, each formed by a different chain, and a long arm composed of all 3 chains. Each laminin chain is a multidomain protein encoded by a distinct gene. Several isoforms of each chain have been described. Different alpha, beta and gamma chain isomers combine to give rise to different heterotrimeric laminin isoforms which are designated by Arabic numerals in the order of their discovery, i.e. alpha1beta1gamma1 heterotrimer is laminin 1. The biological functions of the different chains and trimer molecules are largely unknown, but some of the chains have been shown to differ with respect to their tissue distribution, presumably reflecting diverse functions in vivo. This gene encodes the gamma chain isoform laminin, gamma 3. The gamma 3 chain is most similar to the gamma 1 chain, and contains all the 6 domains expected of the gamma chain. It is a component of laminin 12. The gamma 3 chain is broadly expressed in skin, heart, lung, and the reproductive tracts. In skin, it is seen within the basement membrane of the dermal-epidermal junction at points of nerve penetration. Gamma 3 is also a prominent element of the apical surface of ciliated epithelial cells of lung, oviduct, epididymis, ductus deferens, and seminiferous tubules. The distribution of gamma 3-containing laminins along ciliated epithelial surfaces suggests that the apical laminins are important in the morphogenesis and structural stability of the ciliated processes of these cells.

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Products

Antibodies (43)

Proteins (6)

ELISA Kits (2)

Type

Development Kit (1)

Over-Expression Lysate (2)

Primary (43)

Recombinant (4)

Sandwich (1)

Target

LAMC3 / Laminin Gamma 3 (51)

Reactivity

Human (19)

Mouse (30)

Rat (1)

Chimpanzee (3)

Gibbon (3)

Monkey (3)

Orangutan (3)

Application

IHC (5)

IHC-P (2)

WB (41)

ELISA (3)

IF (3)

Peptide-ELISA (2)

Host

rabbit (35)

mouse (8)

Product Group

DevKit DuoPlus (1)

Isotype

IgG (5)

IgG1,k (8)

Clonality

monoclonal mc (8)

polyclonal pc (35)

Format

96-Well Strip Plate (1)

Antibody Pair and Standard (1)

APC (4)

APC Conjugated (4)

Biotin Conjugated (5)

Cy3 Conjugated (4)

Cy7 Conjugated (4)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (4)

Unconjugated (12)

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Epitope

aa1250-1418 (8)

aa751-875 (8)

aa901-1100 (8)

aa1381-1430 (4)

1330-1410 aa, C-terminal (1)

C-Terminus (1)

Thr1385 (1)

aa1361-1410 (1)

Publications

No (51)

Sample Type

Cell Culture Supernatants (1)

Cell Lysates (1)

Plasma (2)

Serum (2)

Tissue Homogenates (2)

Tag

His (2)

His-GST-S (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Mouse (2)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

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LAMC3 / Laminin Gamma 3 Antibody (aa1361-1410) LS-C119566

Antibody:

LAMC3 / Laminin Gamma 3 Rabbit anti-Human Polyclonal (aa1361-1410) Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, IHC-P, Peptide-ELISA

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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LAMC3 / Laminin Gamma 3 Antibody LS-C663991

Antibody:

LAMC3 / Laminin Gamma 3 Mouse anti-Mouse Monoclonal Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$337; 200 µl/$391; 500 µl/$571; 1 ml/$694; 2 ml/$931; 5 ml/$1,576

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LAMC3 / Laminin Gamma 3 Antibody (HRP) LS-C711025

Antibody:

LAMC3 / Laminin Gamma 3 Mouse anti-Mouse Monoclonal (HRP) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$375; 200 µl/$445; 500 µl/$722; 1 ml/$879; 2 ml/$1,131; 5 ml/$2,048

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LAMC3 / Laminin Gamma 3 Antibody (Biotin) LS-C686743

Antibody:

LAMC3 / Laminin Gamma 3 Mouse anti-Mouse Monoclonal (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$349; 200 µl/$409; 500 µl/$611; 1 ml/$763; 2 ml/$1,001; 5 ml/$1,733

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LAMC3 / Laminin Gamma 3 Antibody (FITC) LS-C693483

Antibody:

LAMC3 / Laminin Gamma 3 Mouse anti-Mouse Monoclonal (FITC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$387; 200 µl/$463; 500 µl/$777; 1 ml/$931; 2 ml/$1,192; 5 ml/$2,205

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LAMC3 / Laminin Gamma 3 Antibody (PE) LS-C725086

Antibody:

LAMC3 / Laminin Gamma 3 Mouse anti-Mouse Monoclonal (PE) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$463; 200 µl/$571; 500 µl/$1,030; 1 ml/$1,201; 2 ml/$1,681; 5 ml/$3,151

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LAMC3 / Laminin Gamma 3 Antibody (APC) LS-C740322

Antibody:

LAMC3 / Laminin Gamma 3 Mouse anti-Mouse Monoclonal (APC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$463; 200 µl/$571; 500 µl/$1,030; 1 ml/$1,201; 2 ml/$1,681; 5 ml/$3,151

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LAMC3 / Laminin Gamma 3 Antibody (APC, Cy7) LS-C741881

Antibody:

LAMC3 / Laminin Gamma 3 Mouse anti-Mouse Monoclonal (APC, Cy7) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$589; 200 µl/$826; 500 µl/$1,441; 1 ml/$1,801; 2 ml/$2,521; 5 ml/$4,725

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LAMC3 / Laminin Gamma 3 Antibody (Cy3) LS-C702001

Antibody:

LAMC3 / Laminin Gamma 3 Mouse anti-Mouse Monoclonal (Cy3) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$463; 200 µl/$571; 500 µl/$1,030; 1 ml/$1,201; 2 ml/$1,681; 5 ml/$3,151

• Unconjugated
• HRP
• Biotin
• FITC
• PE
• APC
• APC, Cy7
• More...
  • Cy3

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE
  • APC
  • APC, Cy7
  • Cy3

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LAMC3 / Laminin Gamma 3 Antibody (1330-1410 aa, C-terminal) LS-C384311

Antibody:

LAMC3 / Laminin Gamma 3 Rabbit anti-Human Polyclonal (1330-1410 aa, C-terminal) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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LAMC3 / Laminin Gamma 3 Antibody LS-C823608

Antibody:

LAMC3 / Laminin Gamma 3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC

Format:

Unconjugated

Price:

100 µg/$357

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LAMC3 / Laminin Gamma 3 Antibody LS-C804045

Antibody:

LAMC3 / Laminin Gamma 3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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LAMC3 / Laminin Gamma 3 Antibody (Thr1385) LS-C193139

Antibody:

LAMC3 / Laminin Gamma 3 Rabbit anti-Human Polyclonal (Thr1385) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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LAMC3 / Laminin Gamma 3 Antibody LS-C752119

Antibody:

LAMC3 / Laminin Gamma 3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

LAMC3 / Laminin Gamma 3 Antibody (aa1250-1418) LS-C295090

Antibody:

LAMC3 / Laminin Gamma 3 Rabbit anti-Mouse Polyclonal (aa1250-1418) Antibody

Reactivity:

Mouse, Rat

Applications:

IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

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LAMC3 / Laminin Gamma 3 Antibody (aa1250-1418, HRP) LS-C711026

Antibody:

LAMC3 / Laminin Gamma 3 Rabbit anti-Mouse Polyclonal (aa1250-1418) (HRP) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639

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LAMC3 / Laminin Gamma 3 Antibody (aa1250-1418, Biotin) LS-C299870

Antibody:

LAMC3 / Laminin Gamma 3 Rabbit anti-Mouse Polyclonal (aa1250-1418) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387

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LAMC3 / Laminin Gamma 3 Antibody (aa1250-1418, FITC) LS-C302028

Antibody:

LAMC3 / Laminin Gamma 3 Rabbit anti-Mouse Polyclonal (aa1250-1418) (FITC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765

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LAMC3 / Laminin Gamma 3 Antibody (aa1250-1418, PE) LS-C725084

Antibody:

LAMC3 / Laminin Gamma 3 Rabbit anti-Mouse Polyclonal (aa1250-1418) (PE) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

• Unconjugated
• HRP
• Biotin
• FITC
• PE

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE

Select

LAMC3 / Laminin Gamma 3 Antibody (aa751-875) LS-C295091

Antibody:

LAMC3 / Laminin Gamma 3 Rabbit anti-Mouse Polyclonal (aa751-875) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

Select

LAMC3 / Laminin Gamma 3 Antibody (aa751-875, HRP) LS-C711024

Antibody:

LAMC3 / Laminin Gamma 3 Rabbit anti-Mouse Polyclonal (aa751-875) (HRP) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639

Select

LAMC3 / Laminin Gamma 3 Antibody (aa751-875, FITC) LS-C693485

Antibody:

LAMC3 / Laminin Gamma 3 Rabbit anti-Mouse Polyclonal (aa751-875) (FITC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765

• Unconjugated
• HRP
• FITC

• Unconjugated
• HRP
• FITC

Select

LAMC3 / Laminin Gamma 3 Antibody (aa1381-1430) LS-C152077

Antibody:

LAMC3 / Laminin Gamma 3 Rabbit anti-Human Polyclonal (aa1381-1430) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

LAMC3 / Laminin Gamma 3 Antibody (C-Terminus) LS-C358790

Antibody:

LAMC3 / Laminin Gamma 3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

30 µl/$255; 100 µl/$299; 200 µl/$351

Select

LAMC3 / Laminin Gamma 3 Antibody (aa901-1100) LS-C374319

Antibody:

LAMC3 / Laminin Gamma 3 Rabbit anti-Human Polyclonal (aa901-1100) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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